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PCSK9 targeting for the treatment of dyslipidemia. reduction of the PCSK9 mRNA I nhibition of the LDLR/PCSK9 binding at the plasma membrane Inhibition of the PCSK9 processing Inhibition of the intracellular LDLR/PCSK9 binding. 1. - PowerPoint PPT Presentation
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PCSK9 targeting for the treatment of dyslipidemia
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1. reduction of the PCSK9 mRNA
2. Inhibition of the LDLR/PCSK9 binding at the plasma membrane
3. Inhibition of the PCSK9 processing
4. Inhibition of the intracellular LDLR/PCSK9 binding
Tibolla G, et al., Nutrition, Metabolism & Cardiovascular Diseases (2011, doi:10.1016/j.numecd.2011.06.002
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