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Nucleotide-based therapeutic agents. MAJOR DRAWBACKS OF ANTISENSE OLIGONUCLEOTIDES. Biologic instability. MAJOR DRAWBACKS OF ANTISENSE OLIGONUCLEOTIDES. Biologic instability Cellular targeting Uptake Efflux from endosomes. MAJOR DRAWBACKS OF ANTISENSE OLIGONUCLEOTIDES. - PowerPoint PPT Presentation
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MAJOR DRAWBACKS OFANTISENSE OLIGONUCLEOTIDES
Biologic instability
MAJOR DRAWBACKS OFANTISENSE OLIGONUCLEOTIDES
MAJOR DRAWBACKS OFANTISENSE OLIGONUCLEOTIDES
INIBIT GENE EXPRESSION
INIBIT PROTEIN FUNCTION
AS-ODN siRNA mAbs Small molecule inhibitors
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