View
1
Download
0
Category
Preview:
Citation preview
Neurulation
NC cells
Fate map of NC cells
Multi-step process of NC induction
EMT
D. Montell
Migratory routes of neural crest cells
1 - Sympathetic ganglia 2 - Sensory ganglia
3 - melanocytes
Migration of cranial NC cells into branchial arches
from Scott Fraser, CalTech
Migration of NC cells from r6 rhombomere
from Scott Fraser, CalTech
The hindbrain
Lineage analysis
Factor
Cell type
Transcription factor
? BMP2/4 GGF WntTGF-β ?
Sensory neurons
Autonomicneurons
Schwanncells
Pigmentcells
Smoothmuscle Cartilage
bHLH proneuralNeuroDNeurogenin
Mash1 Oct-6 nacred/eHAND SOX9
Multipotent neural crest progenitor
Coming up:
3/7 Presentation:(Garcia-Castro et al, 2002)Class discussion:(Lwigale et al., 2004)Lecture:Differentiation
3/10 Lecture:Differentiation cont’dClass Discussion:(Chang et al., 2004)QUIZ
Recommended