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- UV + UV. C. A. - D - D. AG490 MG. ( m M). 132. - D 1 10 100 50 -. 97.1 kDa -. 102 -. C-Term. C-Term. C-Term. C-Term. C-Term. 67.3 kDa -. 71 -. STAT3 a. STAT3 a. STAT3 a. STAT3 a. STAT3 a. 46 -. Cytopl. 43.9 kDa -. (sc-482). (sc-482). (sc-482). - PowerPoint PPT Presentation
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N-Term.STAT3(S21320/610190)
PY 705STAT3(#9131)
STAT1 (+)(sc-346)
STAT5(a+b)(sc-836)
PARP(556362)
-Actin(AC-74)
- D 10 100 250 1 10 60
AG490 z-VAD-FMK(M) (M)
B
A- D - D-UV +UV
97.1 kDa-67.3 kDa-43.9 kDa-
C-Term.
STAT3(sc-482)
97 - 72 - 45 -
29 -
97 - 72 - 45 -
97 - 72 - 45 -
29 -
C-Term.
STAT3(sc-482)
97 - 72 - 45 -
97 - 72 - 45 -
97 - 72 -
45 -
C AG490 MG132
- D 1 10 100 50 -
C-Term.
STAT3(sc-482)
Cytopl.
Nuclei
(M)
102 - 71 - 46 -
28 - 102 - 71 - 46 -
28 -W.T. JAK2+/-
102 -C-Term.
STAT3(sc-482)
71 -
46 -
28 -
+LIF -LIF +LIF -LIFD
C-Term.
STAT3(sc-482)
PY 705STAT3(#9131)
-Actin(AC-74)
121 - 86 - 69 - 52 - 40 - 28 -
E D10L D2In. D3In. D6In.
40 -
+ WT + WT + WT + WT
121 - 86 - 69 - 52 - 40 - 28 -
52 -
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