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Mrs. Griffin
The birds and the bees…
Humans and most other animals reproduce sexually.
This means that two cells fuse to make a new “baby” organism.
These specialized cells are called gametes or sex cells
Sperm and egg cells are human gametes
Meiosis What is it?
Who does it?
Where does it happen?
Why does it happen?
Why is a different process needed?
Making sex cells (sperm and egg)
All sexually reproducing organismsIn males- testes
In females- ovaries
To all organisms to reproduce
1) Chromosome # needs to be cut in half2) Creates genetic diversity
Meiosis
MITOSISDiplo
idzygot
e
Diploid
adult
MEIOSIS
Haploidgamete
s
Remember, humans have 23 pairs of chromosomes
Pairs 1-22 are said to beHomologous chromosomes(they go together becausethey have same traits but arenot identical)
Gene for eye color
Gene for hair color
MeiosisMeiosis is a special kind of cell
divisionthat halves the number of
chromosomesin gametes. This insures that the
correctnumber of chromosomes are
passed on.
The goal is to makehaploid sex cells
First division
Second division
MotherFather
Polar Bodies (not
functional)
What would happen if twocells with 46 chromosomes
fused?
46 chromosomes+
46 chromosomes
92 chromosomes….
Nondisjunction =chromosomes fail to “dis-join” or separate:
Trisomy=gamete with 3 of one type
Monosomy=gamete with 1 of one type
Tripoidy= zygote with three of one type
Down Syndrome= 3 of #21
Karyotype
Klinefelter’s = XXY
Some symptoms… Delayed puberty Loss of libido - reduced interest in sexual activity Impotence Reduced facial hair - reduction in need to shave Tiredness Reduced muscle power and stamina Change in body shape - increased fat and breast
development Infertility Osteoporosis - brittle bones resulting in fractures Depression and sometimes dissocial behavior Early heart disease
Turner’s Syndrome
XO sex chromosome
Instead of XX female
or XY for male
Meiosis has two stages:Meiosis 1and Meiosis 2
Meiosis 1: This is the stage where the chromosome number is halved
Includes 4 stages:Prophase 1Metaphase 1Anaphase 1Telophase 1
Meiosis 1 Prophase 1 is
similar in some ways to prophase in mitosis.Chromosomes
condense
Spindle fibers appear
Nucleus and nucleolus disappear
UNLIKE in mitosis, homologouschromosomes line up next to each other during prophase
•This process iscalled synapsing
•Lined uphomologues arecalled tetrads
When homologous chromosomeshang out so close to each
other,they sometimes swap parts.This is called “crossing over”
Synapsis and Crossing Over in Action
Crossing over increases
genetic diversity
Why is this important
for a species’long-term survival?
During metaphase 1, tetradsline up on a metaphase plate
Then spindle fibers pull thehomologous chromosomes apart inanaphase 1
In telophase 1, two daughter cells are formed. They are NOT identical! (Why?)
After Meiosis 1…
Homologous chromosomes have been separated.
Two non-identical daughter cells have been formed.
The chromosome number has been cut in half.
The big picture
Chromosomes are NOT
duplicated again between
Meiosis 1 and Meiosis 2
Why not?
Meiosis 2 is similar to mitosis Two identical daughter cells are
formed from each of the cells created in Meiosis 1
Includes 4 Stages: Prophase 2 Metaphase 2Anaphase 2Telophase 2
Meiosis II
Meiosis 2 Prophase 2: spindle reforms and
chromosomes move toward the metaphase plate
Metaphase 2: sister chromatids lined up on the metaphase plate
Anaphase 2: sister chromatids are separated and pulled toward opposite poles of the cell
Telophase 2 and Cytokinesis: nuclei form at either pole and each cell is finally divided into two identical daughter cells
All together now…
Let’s compare mitosiswith meiosis…
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