Motor Proteins. One-state model with unequal forward and backward rates

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Motor Proteins

One-state model with unequal forward and backward rates

Dwell time distribution for myosin V

Expected velocity as function of force in one-state model.Comparison to myosin V experiment.

if pulling back makes forward rate go down

if pulling back makes backward rate go up

Pushing by polymerization

Listeria move inside a cell by inducing polymerization of actin

Interpretation as a sloping potential

Model with 2 states at each site.

Velocity of kinesin as a function of ATP conc and load

In two-state model dwell time distribution is not exponential

BA ttt )/exp(1

)( AAA

AA ttp

)/exp(1

)( BBB

BB ttp

)/exp()/exp(1

)()()(0

ABAB

t

ABAAA ttttptpdttp

measured for myosin V

Wave motions in a swimming sperm cell.

Strokes in cilia on epithelial cells

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