Methods of analysing healthcare costs in l ung c ancer CT-screening

Methods of analysing healthcare costs in lung cancer CT-screening

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

Does lung cancer CT screening lead to more healthcare use?

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

Healthcare costs in 12 months

Healthcare costs in 12 months

Healthcare costs in 12 months

Groups analysed:

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

0 1 2 3 4 5 6 7 8 9 10 11

Distribution of Healthcare utilisation in the hospital sector is right skewed

No. of events

Prevalence of healthcare use in the diagnostic groups compared with the control group

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

GP = General Practitioner

The quantity of healthcare use in the diagnostic groups compared with the control group

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

GP = General Practitioner

Prevalence QuantityCumulative

Effect

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

GP = General Practitioner

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

Incl. C

T-sc

reen

ing

scan

Excl. C

T-sc

reen

ing

scan

0200400600800

100012001400160018002000 p<.0001

p=0.52

CT groupControl groupU

SD

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

Mean annual healthcare costs per participant in the control group and the diagnostic groups in the DLCST during five screening rounds

NLST NELSON DLCST0

5

10

15

20

25

Average false-positive rate per screening round

False-positive rate

%

Jakob Fraes Rasmussen, jakobra@sund.ku.dk

NLST: Aberle DR et al. Reduced lung-cancer mortality with low-dose computed tomographic screening. N Engl J Med 2011; 365(5):395-409.

NELSON: van Klaveren RJ et al. Management of lung nodules detected by volume CT scanning. N Engl J Med 2009; 361(23):2221-2229.

DLCST: Saghir Z et al. CT screening for lung cancer brings forward early disease. The randomised Danish Lung Cancer Screening Trial: status after five annual screening rounds with low-dose CT. Thorax 2012; 67(4):296-301.