View
223
Download
0
Category
Preview:
Citation preview
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
1/77
MEDICINE AUTHENTIC ANSWERS WITHREFFERENCE PAGE FROM HARRISON
17TH AND 18TH EDITION
APPG 2013
Medicine and paediatrics
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
2/77
101.h.pylori colonisation is a risk factor for allEXCEPT?
1.adenocarcinoma of distal stomach
2.GERD 3.primary gastric lymphoma
4.auto immune gastritis
Ans 2 and 4 Harrison 17th
Page 947.1870,1871
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
3/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
4/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
5/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
6/77
102.non pancreatic
gastrinomas are
mostly located in
1.duodenum2.stomach
3.liver
4.heartAns 1
Page 2348 table
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
7/77
103.the first choice ofdemardfor initialtreatment of moderate tosevere rheumatiod
arthritis is 1.hydroxychloroquine
2.methotrexate
3.leflunamide
4.gold salts
Ans 2
Page no 2090
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
8/77
104.the most common cause of increasedred cell protoporphyrin levels is
1.absolute or relative iron deficiency
2.vit b12 deficiency 3.sideroblastic anaemia
4.erythropoietic protoporphyria
Ans 1
Page 631
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
9/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
10/77
105.chronic pericardial effusion that is massivebut rarely causes cardiac tamponade is afeature of
1.mycotic infections 2.pyogenic infections
3.rhuematiod arthritis
4.myxoedemaAns 4
Page 1493
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
11/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
12/77
106.the holiday heartsyndrome which typicallyappears after a drinkingbinge manifests most
freqeuntly as 1.heart failure
2.atrial fibrillation
3.complete heart block
4.sudden death
Ans 2
Page 1482
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
13/77
107.one of the following is an esssentialcomponent of multi drug regimen in thetreatment of staphylococcal prosthetic valve
endocarditis 1.gentamycin
2.vancomycin
3.fluroquinolone
4.rifampin(rifampicine)
Ans 4
Page 795 h 17th
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
14/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
15/77
108.autonomic nueropathy type1 or type2DM manifests as all,EXCEPT
1.resting tachycardia
2.sudden death 3.gastroparesis
4.anhidrosis of upper extremities
Ans 4 Page 2289 h 17 th
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
16/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
17/77
109.the most common cause of growth
hormone releasing hormone (GHRH)mediated
acromegaly is
1.hypothalamic tumors
2.choristomas
3.chest or abdominal carciniod tumors
4.neromas
Ans 3
Page
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
18/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
19/77
110.acute kidney injury caused by
acyclovir is due to
1.tubular necrosis
2.tubular obstruction
3.acute interstitial nephritis
4 all the above Ans 3
reference
GOODMAN & GILMAN'S THE PHARMACOLOGICAL
BASIS OF THERAPEUTICS - 11th Ed. (2006
The principal dose-limiting toxicities of intravenous
acyclovir are renal insufficiency and CNS side effects.
Preexisting renal insufficiency, high doses, and high
acyclovir plasma levels (>25 mg/ml) are risk factors for
both. Reversible renal dysfunction occurs in
approximately 5% of patients, probably related to high
urine levels causing crystalline nephropathy.Manifestations include nausea, emesis, flank pain, and
increasing azotemia. Rapid infusion, dehydration, and
inadequate urine flow increase the risk. Infusions should
be given at a constant rate over at least an hour.
Nephrotoxicity usually resolves with drug cessation and
volume expansion. Neurotoxicity occurs in 1% to 4% of
patients and may be manifested by altered sensorium,
tremor, myoclonus, delirium, seizures, or extrapyramidal
signs. Phlebitis following extravasation, rash,diaphoresis, nausea, hypotension, and interstitialnephritis also have been described. Hemodialysis maybe useful in severe cases.
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
20/77
111.lesh-nyhans syndrome is characterisedby all except
1.hyperuricemia
2.self mutilation behaviuor 3.choreo athetosis
4partial deficiency of HPRT
ANS 4 PAGE 2447 h 17th
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
21/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
22/77
112.hyperprolactenemia is caused by allEXCEPT
1.drugs
2.pitutary stalk compression 3.hyperthyriodism
4.renal failure
Ans 3 Page 2205
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
23/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
24/77
113.the drug of chioce in patients with
generalized epilepsy syndromes having mixed
seizure type is
1.phenytion
2.oxcarbazepine
3.lamotrigine
4.valproic acid
Ans 4
Page 2509 h 17th
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
25/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
26/77
114.most cases of hemifacial spasms arerelated to
1.sequeale of bells palsy
2.secondary to compression of nerve bytumor
3.multiple sclerosis
4vascular compression of facial nerve inpons
Ans 1
Page 2585
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
27/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
28/77
115.the most common cause ofcardioembolic stroke is
1.rhuematic heart disease
2.non rhuematic atrial fibrillations 3.myocardial infraction
4.mitral valve prolapse
Ans 2 Page 2517
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
29/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
30/77
116.extra renal manifestations of autosomaldominant polycystic kidney disease(ADPKD)includes all EXCEPT
1.saccular anuerysms 2.aortic root and annulus dilatations
3.colonic diverticulae
4.splenic cysts
Ans 4
Page 1798 h 17th
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
31/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
32/77
117.focal seizures in bacterial meningitis areusually due to
1.cortical venous thrombosis with
haemorrage 2.hyponatremia
3.cerebral anoxia
4.toxic effects of high dose pencillinAns 1
Page
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
33/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
34/77
118.patchy specific lesions seen on smallbowel biopsy includes all EXCEPT
1lymphoma
2.whipples disease 3.amyloidosis
4 eosinphilic gastroenteritis
Ans 2 Page 1880
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
35/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
36/77
119
Which one of the following significantly reducesplasma levels of lp(a) upto 40%
1.HMG COA reductase inhibitors 2.fibric acid derivatives
3.nicotinic acid
4.bile acid sesuestrantsAns 3
Page
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
37/77
Wikipedia given only 20 to 30% for nicitinic
acid
I didnt information in 17 th and 18th harrison
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
38/77
120.in patients with severe structural lungdisease ,such as bronchectasis or severecopd,the infective agent most likely to causepneumonia is
1.h.influenza
2pnuemococcous
3.legionella
4.p.aeruginosa
Ans 4
Page 1629
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
39/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
40/77
121.the most common life threatening metaboliccomplication of squamous cell carcinoma oflung is
1.hyponatremia 2.hypercalcemia
3.hypokalemia
4.hypomagnesemia
Ans 2
Page 2306
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
41/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
42/77
122.the predominant causeof diarrhoea among elederlypatients in chronic careinstitutiins is
1.enteropathogenic e. coli
2.shigella 3.c .difficle
4.klebsiella
Ans 3
Harrison 18th editin lines
Enteropathogenic E. colihasbeen associated withoutbreaks of diarrhea innurseries for newborns. One-third of elderly patients inchronic-care institutionsdevelop a significantdiarrheal illness each year;more than one-half of thesecases are caused bycytotoxin-producing C.difficile.Antimicrobial therapycan predispose topseudomembranous colitis byaltering the normal colonicflora and allowing themultiplication ofC. difficile(Chap. 129).
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
43/77
123.in bronchiectasis pedominantinvolvement of central airways is seen in
1.allergic bronchopulmonary aspergillosis
2.infection with m avium complex 3.cystic fibrosis
4tuberculosis
Ans 1 Page 1259
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
44/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
45/77
124.all the sideeffects of interferon theray arereversible upon dose lowering or cessation oftherapy EXCEPT.
1alopecia 2.diarrhoea
3.autoimmune thyrioditis
4.tingling of extremities
Ans 3
Page see below
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
46/77
Complications of IFN therapy includesystemic "flu-like" symptoms; marrowsuppression; emotional lability (irritability,
depression, anxiety); autoimmune reactions(especially autoimmune thyroiditis); andmiscellaneous side effects such as alopecia,rashes, diarrhea, and numbness and tingling
of the extremities. With the possibleexception of autoimmune thyroiditis, allthese side effects are reversible upondose lowering or cessation of therapy.
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
47/77
125.in juvenile pernicious anemia all arepresent EXCEPT
1.gatric atrophy
2.achlorhydria 3.serum IF antibodies
4parietal cell anti bodeis
Ans 4 Page 648
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
48/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
49/77
126.a unique form of hemolytic anemia (withspur cells and acanthocytes) can occur inpatiens with sever alcoholic hepatitis is called as
1.kostmanns syndrome 2.zieves syndrome
3.seckel syndrome
4dubowitz syndrome
Ans 2
Page 1972
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
50/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
51/77
127.in vertebral osteomylitis,anterior erosions ofthe superior end plate of vertebrae are typicallythe first feature to become evident in
1.typhiod 2 tuberculosis
3.brucellosis
4.staphylococcal osteomylitis
Ans 3
Page 804
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
52/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
53/77
128 aplstic anemia with pancreaticinsufficiency and malabsorption is seen in
1.fanconis syndrome
2.dyskeartosis congenita 3.shwachmann diamond syndrome
4 diamond blackfan syndrome
Ans 3 Page 665
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
54/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
55/77
129.the areas most often involved in lesionsof toxoplasmosis in CNS includes allEXCEPT
1brain stem 2.meninges
3.basal ganglia
4.pitutary glandAns 2
Page 1308
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
56/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
57/77
130.autosommal reccessive hyperig Esyndrome is charecterised by all EXCEPT
1.recurrent bacterial infections of skin and
respiratory tract 2severe allergic manifestations
3.T & B lymphocyte count are low
4.deficiency in tyk2,a JAK family kinase
Ans 4
page
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
58/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
59/77
131. All are primary causes of nephroticsyndrome in infants younger than one year,EXCEPT
A. Congenital nephrotic syndromeB. Minimal change diseaseC. Membranous nephropathy.D. Systemic lupus erythematosusAns d
Page robbins 7th edition
979
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
60/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
61/77
132. Regarding Reye syndrome, all of the followingstatements are TRUE, EXCEPT
A. The white liver disease and encephalopathy withfatty degeneration of the viscera are its other
nomenclaturesB.Sporadic Reye syndrome can occur in the contextof varicella or influenza B virus infectionC. The condition is usually observed in children below3 years of ageD. Mitochondrial dysfunction of fatty acid oxidation issignificant
Ans c
Page 524 op ghai
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
62/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
63/77
133. Hemorrhagic cystitis is a dreadedcomplication associated with use of
A. ClobazamB. CyclosporinC. CycloserineD. Cyclophosphamide
Ans d Page katzung 885
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
64/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
65/77
134. An 18 month old boy presents with prominenteyeballs and periorbital ecchymosis and an enlargingswelling on the left upper abdomen. He is markedly pale.A large left sided mass distinct from the spleen waspalpable. The most likely diagnosis is
A. Wilm's tumorB. OsteopetrosisC. NeuroblastomaD. Gauchers Disease
Ans C Page op ghai
573
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
66/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
67/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
68/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
69/77
135. One of the following intrauterine infectionshas characteristically the following triad ofchorioretinitis, microcephaly and intraceiebralcalcifications.
A. CytomegalovirusB. Toxoplasmosis ,C. RubellaD. Herpes simplexAns A pg 1110 harrison 17th
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
70/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
71/77
136. A 5 year old girl has 3 months history of joint painsand morning stiffness. Knees and ankles are involvedwith mild swelling and tenderness. Slit lamp examinationreveals IRIDOCYCLITIS. The diagnosis is
A. Juvenile Rheumatoid Arthritis (JRA)B. Systemic Lupus Erythematosus (SLE)C. Henoch Schonlein Purpura (HSP)D. Rheumatic Arthritis
Ans A
581
Op ghai
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
72/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
73/77
137. A 7 year old/ boy has short stature,large skull, prominent forehead, saddleshaped nose, exaggerated lordosis andnormal intelligence and development, thediagnosis is
A. Noonan syndrome
B. HypopituitarismC. Isolated Growth Hormone V DeficiencyD. Achondroplasia
Ans D
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
74/77
138. Immediately after birth, the preventablecauses of mental retardation include all of thefollowing, EXCEPT
A. HypothyroidismB. Phenylketonuria.C. KernicterusD. Hurlers disease
Ans d
545 op ghai
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
75/77
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
76/77
139. Which of the following is associated withlarge anterior fontanel ?
A. AchondroplasiaB. Apert syndrome
C. Cleidocranial Dysostosis
D. All of the aboveAns D
7/29/2019 Medicine Authentic Answers With Refference Pages From Harrison 17th
77/77
140. An aggressive looking, thin and talladolescent boy aged 15 years is noted tohave prominent long limbs and small testes.What is the most relevant investigation ?
A. Hormonal assaysB. Chromosomal analysis
C. Skeletal surveyD. Ultrasound evaluation
Ans b
Recommended