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MBS Seminar Announcement
June 5th, 2014College of Veterinary MedicineResearch Building, Room 101
12:15 PM
Research abstract: In regenerative medicine, a critical hurdle for the development of clinically relevant applications is the lack of appropriate large animal models. Two species, dog and swine, provide di�erent, yet unique opportunities. Swine are physiologically similar to humans and can be genetically manipulated at high e�ciency. Our work in this area has allowed us to generate complex transgenic lines including the generation of a severe combined immune de�cient (SCID) pig that can be used to host xenogeneic cells. The dog, in contrast, is an excellent model of naturally occurring diseases and as such is a great translational model for developing cell-based therapies in a clinical setting. Our work in this area focuses on identi�cation of ideal conditions for the isolation and maintenance of stem cells. This seminar will summarize some of our work in these areas.
Web site: http://www.cvm.ncsu.edu/mbs/personnel/piedrahita_jorge.html
“Large Animal Models in Regenerative Medicine: A Tale of Two Species”
Jorge Piedrahita, PhDDirector, Center for Comparative Medicine and Translational
ResearchProfessor, Dept. of Molecular Biomedical Sciences
North Carolina State University
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