LOGAN INSTRUMENTS CORP. - DCtech€¦ · Automated Dissolution Syringe Pump Sampling System . Media...

LOGAN INSTRUMENTS CORP. 19-C Schoolhouse Rd, Somerset New Jersey 08502 USA

Implants

A. Gastrointestinal B. Transdermal C. Implants

Dissolution Testing

By Dr. Luke Lee

A. In- Vitro Gastrointestinal

USP Apparatus 1,2,

USP Dissolution Method 1

12 position dissolution testers

Color touch screen display

Automated Sampling Manifold

Syringe holder

Auto dropping tray & vessel cover

UDT-804-2L Universal Dissolution

Tester

2L Dissolution Tester

UDT-804-4L Universal Dissolution

Tester

4L Dissolution Tester

UDT 816D-12/12T

12 position AIRBATH dissolution tester with 3 speed

12 vessel Temp. reports

3 Speed zones

No water bath

SYSTEM 800S Automated Dissolution UV on-line System

SYSTEM 850BDL For HPLC off line analysis

Automated Dissolution Syringe Pump Sampling System

Media replacement lines

To collector

SYSTEM 850BDL - 4 bath sampling loop

Bath 2.

Bath 4.

Bath 3.

Bath 1.

DSC-800 System Controller

SYSTEM 850BDL-12 For HPLC off line analysis

Automated Dissolution Syringe Pump Sampling System

SYSTEM 850BDL-12 X 2 Automated Dissolution Syringe Pump Sampling System (Made in the USA)

SYSTEM 860D-12CDL Automated AIRBATH Dissolution Syringe Pump Sampling System

LOGAN SYSTEM 860CDL-12 Automated 3 Speed Zones Dissolution Sampling System with

Center-Point™ Camera

UDT-816 Universal Dissolution Tester

Syringe Pump / System Controller

Auto-sampler Camera System

LOGAN UDT-816

3 Speed Zones Universal Dissolution Tester With Center-Point™ Camera

For PADDLE TEST - Center-Point™ camera is located at the bottom of bath center to the vessel

LOGAN UDT-816

3 Speed Zones Universal Dissolution Tester

With IN-SHAFT camera for basket

For BASKET TEST - Camera is located inside the basket shaft

SYSTEM 860D-12CDL Automated AIRBATH Dissolution Syringe Pump Sampling System w/Cameras

Tablet in

Basket Test

Tablet in

Paddle Test

MDS 600PL

Media Delivery System

• The mobile unit brings pre-heated,

degassed media to dissolution testers.

• Fills 6 vessels to the same volume

simultaneously.

• Media de-aerated by heat, high speed

circulation, filtration and vacuum.

• Temperature accuracy controlled to +/-

0.2 C.

• Simultaneously delivers 6 vessels up

to 1000 ml within 2 minutes

• Detachable Oxygen meter to check

oxygen

• Printer report for Date, Time, Media

Type, Media Volume, Temperature,

Oxygen Dissolving Rate, pH, etc.

MDS 600PL

Media Delivery System Vacuum & Measurement Chambers

MDS 600PL

Media Delivery System

MDS-600 Delivery Manifold

UDT-804 Dissolution Tester

MDS 600T

Bench Top Media Delivery System

AVC-100 HTP Automated Vessel Cleaner

• For validation

• Color Touch Screen Display

• Mobile unit brings cleaner to bath

• Selectable methods for different products,

• High pressure turbo wash and vacuum

• Media neutralization in waste tank

• Automatic waste discharge

AVC-100 HTP Automated Vessel Cleaner

Wash Head

UDT-814 Dissolution Tester

USP Dissolution Apparatus 3

For USP Method 3 Tests

In line

sampling

Individual vessel

covers

LOGAN AUTOMATED DISSO III-7

SYSTEM

Flow Cell

Piston Pump

To WasteFraction Collector

Splitter

Fresh Medium

Open Loop System

Close Loop System

• Peristaltic Pump

• Syringe Pump

• Piston Pump

Tablet cell12 mm

Cell forimplants

Cell forointments

and creams

Tablet cell22.6 mm

Cell forsuppositories

and softgelatin capsules

Cell forpowders

and granulates

Logan DRY HEAT USP 4 Sampling Systems

Transdermal Diffusion Cell

Testing

By Dr. Luke Lee

B. Transdermal

APPLICATION AREAS : • Hair • Eyes • Nose • Mouth • Nails • Skin--- Most popular area– 2 sq meters per human

What are the products that need transdermal testing?

Users of Transdermal Systems

How to perform Transdermal Testing?

•Transdermal Diffusion Cells •Skin / Membranes •Drive Consoles

Topical: Temperature 32 C The drug stays on the surface of the skin or is absorbed by skin

Transdermal: Temperature 37 C The drug penetrates the skin and gets into blood stream

Transdermal Diffusion Cells :

Vertical cell / Franz Cell

LOGAN vertical Cell

Logan nail cells

Nail holder

LOGAN Horizontal Cells / Side By

Side Cells

Logan cornea cells

Horizontal Cells / Side By Side Cells

Artificial Skin – Strat-M membrane

Strat-M Membrane

2. Place the Strat-M Membrane on the Diffusion cell

Strat-M Membrane

3. Load samples on Strat-M Membrane

All cells must be clean

Media Degassing Station

Degassing Media

LOGAN FDC-6

Transdermal diffusion cell drive console

Temperature Controller

FDC-6 Drive Console

Franz cells

LOGAN SDC-6

Transdermal Diffusion Cell Drive Console ( 6 Side By Side Cells)

LOGAN SFDC-6

Transdermal Diffusion Cell Drive Console ( 3 Verital Cells & 3 Side By Side Cells)

LOGAN DHC-6T

Dry Heat Transdermal System

LOGAN DHC-6T

For sampling, the cell support plate lays flat

LOGAN DHC-6T

For media replacement, the cell support plate tilts to purge the bubbles

LOGAN FDC-6T

Semi- Automated System

LOGAN FDC-6T

Semi-Automated Systems

LOGAN SYSTEM 913-12 Automated Transdermal

Diffusion Cell System

SYRINGE

SCT- DL SAMPLE

COLLECTOR

SYSTEM CONTROLLER

FDC-6T DIFFUSION CELL DRIVE CONSOLE

LOGAN SYSTEM 914-12 Automated Transdermal

DRYHEAT Diffusion Cell System

SYRINGE

SCT- DL SAMPLE

COLLECTOR

SYSTEM CONTROLLER

DHC-6T DIFFUSION CELL DRIVE CONSOLE

DEAR-1200 ONLINE DIGASSING SYSTEM (Optioanl)

DEAR-100 w/ Vacuum bottle

Heat Plate (Not included)

LOGAN SYSTEM 912

Automated Transdermal Diffusion Cell

Sampling System

USP Apparatus 5,6,

For USP Dissolution Apparatus 4 & 7

C. Implants / Suspensions

Logan Suspension Test Sampling Systems

Logan Suspension Cells

Logan Suspension Test Sampling Systems

LOGAN DISSO III-7 Rate Tester

USP 7 Balloon Holders

USP 7 Sample Holders

USP 7 Sample Holders & vessels

Glass Tubes

250 ml Glass Tube 50 ml Glass Tube

LOGAN DISSO III-7 USP 7 Tube Carrier—7

50 ml tubes for small volume media

150-250 ml media in the 300 ml

DISK for smaller patched

LOGAN SYSTEM 7000-24

Automated USP 7

Heart Stents Test System

LOGAN Fully Automated USP 7 System

LOGAN SYSTEM 7000-24

Automated USP 7

Hip Stem Test System

LOGAN SYSTEM 7000-24 Automated Hip Stem Test System

USP Physical Testers

DST-3/6 Disintegration Tester

•Easy-To-Use input keypad

•Audible end of run signal

•Modular design for 1 to 6

simultaneous tests

• 2 Single in-line layout for easy

viewing of all basket assembles

•Meets and exceeds all USP

requirements and

specifications

FAB-2S Friability Tester

•As per USP specification

•Adjustable speed at 20-70 rpm

•Test with one or two drums

•Select counter or timer

•Easy input key pad

•Microprocessor control & LCD

display

FAB-2SP Friability Tester

•As per USP specification

•Adjustable speed at 20-70 rpm

•Test with one or two drums

•Select of counter or timer

•Easy input key pad

•Microprocessor control & LCD

display

•Printer / report center

LOGAN HDT-400L

Automated Hardness Tester For: Hardness / Thickness / Diameter / Weight measurements

LOGAN TAP-2S Automated Tap Density Tester

Meets all current USP, BP, JP

guidelines.

LED Display for TIME or

COUNTER.

Microprocessor Technology

Control System.

Easy To Use Input Keypad.

Modular Design for One or Two

Platforms.

Simultaneous tapping and rotary

motion

LOGAN TAP-2SP Automated Tap Density Tester w/ Printer

Meets all current USP, BP, JP

guidelines.

LED Display for TIME or COUNTER.

Microprocessor Technology

Control System.

Easy To Use Input Keypad.

Modular Design for One or Two

Platforms.

Simultaneous tapping and rotary

motion

Report printer

Thank you! Prepare by Dr. Luke Lee

www.loganinstruments.com www.loganinstruments.cn

LOGAN INSTRUMENTS CORP. - DCtech€¦ · Automated Dissolution Syringe Pump Sampling System . Media...

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