View
27
Download
0
Category
Tags:
Preview:
DESCRIPTION
INSULIN. Fyn. Nck. SHC. GRB2. GLUT4. SOS. IRS1. Flotillin. Crk. Ras. GTP. CAP. Rab4. PI3K. GRB10. APS. GLUT4 Vesicle. Raf. IRS1/2. SHC. PPtase1. c-CbI. MEKs. Akt PKB. Rac. Insulin. JNK. PDK. PKC. mTOR. Insulin. P. P. P. P. P. P. P. P. P. P. P. P. P. P. - PowerPoint PPT Presentation
Citation preview
P
P
P
P
P
P
P
P
P
GlycogenSynthaseGlycogenSynthase
c-Jun
EEF2K
eIF4
EEF2
TranslationAnti-apoptosis
Gene Expression
Translation
Fatty AcidSynthesis
ATP
C
itrat
e ly
ase
Glucose
EBSEBS
GeneExpression
GeneExpression
P
P
p70S6K
JNK
eIF4EBP Insulin Degradatio
n
& Receptor
Dephosphorylation
Insulin Degradatio
n
& Receptor
Dephosphorylation H+H+
eIF2B
BAD
14-3-3
BAD
MEKs
ERKs
PKC
P
PP
PAPS
c-CbI
PPtase1
GSK3
Nck
IRS1
SHCP
P
PCrk
SOS
GTP
mTOR
FKHRL1
Lipid RaftLipid Raft
Flotillin
RasCAP
GLUT4Translocation
TRETRE
GRB10
INSULININSULIN
Receptor
Internalizatio
n
Receptor
Internalizatio
n
Elk
c-Fos
InsulinReceptorInsulin
Receptor
PIP3 PIP2
AktPKB
H+
EAI
EAIInsulinInsulin
S6
Rac
PI3K
PDK
GLUT4GLUT4
GRB2
Fyn
lnsulin Receptor Pathway
RafGLUT4VesicleGLUT4Vesicle
c-CbI
InsulinInsulin
P
SHCIRS1/2
PIP2
PIP3
Rab4
P
P
P
P
P
P
P
P
P
GlycogenSynthaseGlycogenSynthase
c-Jun
TranslationAnti-apoptosisGene ExpressionTranslationFatty AcidSynthesis
Glucose
GeneExpression
GeneExpression
JNK
Insulin Degradatio
n
& Receptor
Dephosphorylation
Insulin Degradatio
n
& Receptor
Dephosphorylation H+H+
PKC
P
PP
P
APS
c-CbI
Nck
IRS1
SHCP
P
P Crk
Lipid RaftLipid Raft
Flotillin
CAPGLUT4
Translocation
TRETRE
INSULININSULIN
Receptor
Internalizatio
n
Receptor
Internalizatio
n
c-Fos
InsulinReceptorInsulin
Receptor
PIP3 PIP2
H+
EAI
EAIInsulinInsulin
Rac
PI3K
GLUT4GLUT4
GRB2
Fyn
lnsulin Receptor Pathway.A SIMPLIFIED VERSION
GLUT4VesicleGLUT4Vesicle
c-CbI
InsulinInsulin
P
SHCIRS1/2
PIP2
PIP3
Rab4
Cell membrane
Nucleus
Recommended