Lecture22 Genetic Networks Lac Operon - ManningGroup · 2018-11-27 · OPERON OFF because Lac...

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Lecture 22:Genetic networks and the Lac Operon

Reading: PBC Chapter 6.1.2PBC Chapter 19

Recall:

Now what if we add regulation: repressors and

activators?

Repressors

TetR

IdeR

FadR

PurR

Examples of actual repressors

CAP

p53 tumor supressor

zinc finger DNA binding domain

leucine zipper DNA-binding domain

Examples of actual activators

The lac operon

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