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Intro to AAPSfor students,student chapters,prospect membersTuesday, October 6. 2015
Introduction
Presenters:
Shraddha Thakkar, BIOTEC
Katie Maass, SPOD
Vibhuti Agrakari, SPOD
Paddy Eangoor, APQ
Tanzir Mortuza, BIOTEC
Amelia Deitchman, CPTR
Johannes Kast, CPTR
Rachel Saylor, DDDI
Manjeet Pimparade, FDD
Yamini Gorantla, MSE
Sophia Fong, PPB
Nicole Zane, PPDM
Anqi Wan, RS
AAPS Mission and VisionMission
AAPS advances the capacity of pharmaceutical scientists to develop products and therapies that improve global health.
Vision
AAPS will advance the pharmaceutical sciences to drive prevention and cures.
Core Values
Learning
Innovation
Service
Inclusiveness
Integrity
AAPS Students and Postdoc Membership
1,825 Student Members
401 Postdoc Members6303
2225
Student/PostDoc Membership comprise 25% of all AAPS Membership
Regular Members Student/Postdoc Members
Over 100 AAPS Student Chapters across the world
Webinar OverviewAAPS provides robust networking community and countless opportunities: AAPS Sections Focus Groups Education and Resources Student/Postdoc Outreach Committee Career Center
Introduction to AAPS Sections & Focus Groups
AAPS Sections Groups with interests in broad areas
of pharmaceutical sciences. Responsibility for governance Broad in scientific scope, Share research Serve on AAPS committees Participate in meetings and workshops
Section Offerings for students
AAPS Mentoring Travelships Awards Moderating Opportunities
AAPS Sections APQ —Analysis and Pharmaceutical
Quality section
BIOTEC — Biotechnology section
CPTR — Clinical Pharmacology and Translational Research section
AAPS Sections
DDDI — Drug Discovery and Development Interface section
FDD — Formulation Design and Development section
MSE — Manufacturing Science and Engineering section
AAPS Sections PPB — Physical Pharmacy and
Biopharmaceutics section
PPDM — Pharmacokinetics, Pharmacodynamics, and Drug Metabolism section
RS — Regulatory Sciences section
AAPS Student Membership
APQ6%
BIOTEC10%
CPTR10%
DDDI11%
FDD32%
MSE5%
PPB11%
PPDM13%
RS3%
Students on AAPS Sections
AAPS Focus Group Within each section are multiple focus
groups (FG) There are over 40 focus groups FG can be shared by multiple sections Collaboration opportunities Networking opportunities
DDDI
Primary FG: Discovery Model & Simulation Other affiliated sections: PPDM, PPB
APQPRESENTER: PADMANABHAN (PADDY) EANGOOR, MERCER UNIVERSITY
APQ—Analysis and Pharmaceutical Quality section
Goals: Provide a forum for the exchange of information pertaining to analytical techniques, bioanalytical techniques, regulatory and compendial issues, and assurance of quality
Leadership: Chair: Peter D. Bryan, Ph.D. Chair-elect: Dilip R. Choudhury, Ph.D. Vice-chair: Eliza Fung, Ph.D. Secretary/Treasurer: Mark E. Arnold, Ph.D. Past chair: Kenneth Jay Norris, M.S.
Student representative: Paddy Eangoor (Mercer University)Paddy’s recent blog post: Turning Point of a Graduate Student
Members: 2159Student members: 208
APQ—Analysis and Pharmaceutical Quality section
Primary focus groups Bioanalytical
Contract Research Organization (CRO)
In Vitro Release and Dissolution Testing
Non-clinical Dose Formulation and Analysis
Pharmaceutical Impurities
Stability
Secondary focus groups
Chemical and Biological Active Pharmaceutical Ingredient Manufacturing Technology
Biosimilars
Chemistry, Manufacturing, and Controls (CMC)
CMC Statistics
Generic Pharmaceuticals
Ligand Binding Assay Bioanalytical
Microdialysis
Nutraceuticals and Natural Products
Process Analytical Technology
APQ—Analysis and Pharmaceutical Quality section
Opportunities:
Mentoring program Student travelships to attend annual meeting Awards at the Annual meeting
AAPS APQ Best Poster Award AAPS Graduate Student Research Awards in
Analysis and Pharmaceutical Quality AAPS Outstanding Manuscript Award in Analysis
and Pharmaceutical Quality APQ Research Achievement Award
More opportunities
Webinars and interviews with thought leaders of APQ section
APQ newsletter: Volunteers can contribute
AAPS APQ Education initiation award
Planning for a robust APQ Student Section Committee Seeking volunteers to serve on the committee
Volunteer opportunities in affiliated focus groups
For more information about APQ section, please visit: https://www.aaps.org/APQ/
APQ—Analysis and Pharmaceutical Quality section
BIOTECPRESENTER: TANZIR MORTUZA, UNIVERSITY OF GEORGIA
BIOTEC—Biotechnology Section
Vision: Unite multiple scientific disciplines in a forum where experimental results and experiences are shared and evolving concerns on the research, development, and manufacture of biotechnology based pharmaceuticals are discussed
BIOTEC—Biotechnology Section
BIOTEC Leadership – Chair - Gopi Shankar, Ph.D., MBA
Chair-elect - Meena Subramanyam, Ph.D.
Vice Chair - Scott Fountain, Ph.D.
Secretary/Treasurer - Boris Gorovits, Ph.D.
Past Chair - Tapan K. Das, Ph.D.
BIOTEC—Biotechnology Section
Current Student Committee (BSSC) Chair – Tanzir Mortuza (University of Georgia) Secretary – Katherine Hickey (West Virginia
University) NBC Liaison – Fizal Nabbie (University of
Science Philadelphia) Student Rep – Hardik Mody (Ohio State
University)
BIOTEC—Biotechnology section Opportunities for students Mentor and Mentee opportunity
25 matches
Matches were based on interests and geographical locations
Student Rep opportunity For primary and secondary focus group
Placed student rep for Ligand Binding Assay Bioanalytical FG (LBABFG)
Student Professional Development Webinar – April 15th, 2015
The Do’s and Don’ts that Define Success for Academic Job Applications
Speakers – Dr. Christopher McCurdy (University of Mississippi) & Dr. Brian Cummings (University of Georgia)
BIOTEC—Biotechnology section More Opportunities Awards and Travelships – Travelships up to
$750 (graduate/undergraduate students, postdocs eligible)
AAPS Graduate Student Research - Award in Biotechnology sponsored by Janssen
Newsletter/ Blog contribution BIOTEC Section Townhall Meeting and
Reception at 2015 Annual Meeting
BIOTEC—Biotechnology section
Future Goals: 1 more Webinar before end of the year
2 Student Development Webinars for year 2015-2016
Increase student participation in BIOTEC
25 Co-moderator placement at Annual Meeting
Initiate mentor-mentee interactions
BIOTEC—Biotechnology section
Primary Focus Groups
Biosimilars
Ligand Binding Assay Bioanalytical
Protein Aggregation and Biological Consequences
Therapeutic Product Immunogenicity
For more information about APQ section, please visit: http://www.aaps.org/BIOTEC/
CPTRPRESENTER: AMELIA DEITCHMAN & JOHANNES KAST, UNIVERSITY OF FLORIDA
CPTR—Clinical Pharmacology and Translational Research section
Vision“The AAPS CPTR section is dedicated to clinical and translational research and development of human pharmaceutical products, particularly related to issues of clinical pharmacology or applied pharmacotherapy (including adverse drug reactions and special populations), clinical pharmacokinetics and pharmacodynamics, clinical trial design and simulation, pharmacogenomics, and contract research of human pharmaceuticals. The scope of the CPTR section extends beyond the development of human pharmaceuticals into the postmarketing phase and ultimately the clinical performance of medicines administered to patients.”
CPTR—Clinical Pharmacology and Translational Research section
Leadership Chair: Alexander Vinks, PharmD, PhD, FCP (Cincinnati's
Children’s Hosipital)
Chair-elect: Arnab Mukherjee, PhD (Pfizer)
Vice Chair: Adel H. Karara, PhD, FCP (U Maryland Eastern Shore)
Secretary/Treasurer: John D. Davis, PhD (Regeneron)
Past Chair: Joan M. Korth-Bradley, PharmD, PhD (Pfizer)
Student Representatives: Amelia Deitchman, PharmD (University of Florida)
Johannes Kast, RPh (University of Florida)
CPTR—Clinical Pharmacology and Translational Research sectionOpportunities for Students Mentoring Program (mentors from across the
pharmaceutical industry, regulatory, and academic settings)
Student Travelships & Awards AAPS Graduate Student Research Awards in PPDM &
CPTR (Sponsored by Eli Lilly)
CPTR—Clinical Pharmacology and Translational Research section
Primary
Biomarkers in Translational Medicine
Pharmaceuticals in Global Health
Pharmaco-imaging
Pharmacogenomics (PGx)
Pharmacometrics
Systems Pharmacology
Secondary
Animal Pharmaceutics & Technology
Drug Transport
Microdialysis
Protein Aggregation and Biological Consequences
Therapeutic Product Immunogenicity
Focus Groups
For more information visit: http://www.aaps.org/CPTR/
DDDIPRESENTER: BRITTANY DUERK SPITZNAGEL, LIPSCOMB UNIVERSITY
Goal: DDDI focuses on issues at the critical interface between drug discovery and drug development and provides a collaborative forum for interactions among scientists from academia, industry and government institutions.
Leadership:
Chair: Susan L. Mercer, Ph.D. Chair-elect: Robin M. Zavod, Ph.D. Vice Chair: Caroline McGregor, PhD Secretary/Treasurer: David A. Colby, Pharm.D., Ph.D.
Student Rep: Rachel Saylor (University of Kansas)
DDDI—Drug Discovery andDevelopment Interface section
DDDI—Drug Discovery andDevelopment Interface section
Secondary Drug Metabolism
Drug Transport
Nanotechnology
Oral Absorption
Pharmaco-imaging
Pharmacogenomics (PGx)
Targeted Drug Delivery and Prodrug
Focus GroupsPrimary Discovery Modeling
and Simulation
Drug Candidate Selection
Nutraceuticals & Natural Products
Opportunities for students DDDI Mentoring Program Awards/Travelships DDDI newsletter and eBlast Planning for a DDDI Student Section Committee Volunteer opportunities in affiliated focus groups
DDDI—Drug Discovery andDevelopment Interface section
For more information visit: http://www.aaps.org/DDDI/
FDDPRESENTER: MANJEET PIMPARADE, UNIVERSITY OF MISSISSIPPI
FDD—Formulation Design and Development section Vision: The Formulation Design and Development section will be the premier worldwide forum for scientists dedicated to the design and development of all dosage forms for drugs, biologics, and combinations thereof as well as drug/biologic device combinations.
Leadership
Chair: Panayiotis P. Constantinides
Chair-elect: Joseph P. Reo
Vice-chair: Jeffrey Hemenway
Secretary/Treasurer: Linda A. Felton
Past-Chair: Michael A.Repka
Student Representative: Manjeet B.Pimparade (Ole Miss)
FDD—Formulation Design and Development section
The FDD section benefits its members both personally and professionally through various activities.
Awards/Fellows/Travelship
Communication
Education
Focus Groups
Volunteer Opportunities
Opportunities for students
FDD—Formulation Design and Development section
Primary Animal
Pharmaceutics and Technology
Dermatopharmaceutics Excipients Inhalation and Nasal Technolog
y
Lipid-Based Drug Delivery Systems
Modified Release Ocular Drug Delivery & Disposit
ion
Patient-Centric Drug Development, Product Design, and Manufacturing
QbD and Product Performance Sterile Products
Focus Groups
Secondary In Vitro Release and Dissolution T
esting
Nanotechnology Nutraceuticals and Natural Produ
cts
Preformulation Process Development Process Modeling and Simulation Contract Research Organization (
CRO)
For more information visit: http://www.aaps.org/FDD/
MSEPRESENTER: YAMINI GORANTLA, MERCER UNIVERSITY
MSE—Manufacturing Science and Engineering sectionVision: The Manufacturing Science and Engineering section will be recognized globally as the premier organization of individuals dedicated to the advancement of science and engineering as applied to the design and manufacture of investigational and commercial pharmaceutical and pharmaceutically related products.
Leadership:
Chair : Vidya Swaminathan
Chair-elect : Ruta Y. Waghmare
Vice Chair : Sharmista Chatterjee
Secretary/Treasurer: Claire Scanlan
Past Chair: Tom Sam
Student Representative: Yamini Gorantla (Mercer University)
MSE—Manufacturing Science and Engineering section
Provide a forum for open interchange and dissemination of scientific knowledge and technical advances related to manufacture of pharmaceutical and pharmaceutically related products.
Provide timely programming, strong networking and membership interactions, recognition of scientific achievement, and vigorous inter-organizational collaboration.
Foster graduate education, career growth, and professional development of the membership while promoting continued growth and implementation of science and technology as applied to manufacturing.
Collaborate with other AAPS sections, focus groups, and other scientific organizations associated with the development, registration, control, production, and troubleshooting of pharmaceutical products.
Recognize excellence and achievement of its members, encourage programming and publication of manufacturing-related scientific works by its members in AAPS-sponsored journals, and fosters graduate education and career growth and development of MSE members.
Goals
MSE—Manufacturing Science and Engineering sectionFocus Groups
Primary Chemical and biological
active pharmaceutical ingredient manufacturing technology
Process Analytical Technology
Process Development
Process modeling and simulation
Secondary Chemistry, Manufacturing
and Controls(CMC)
CMC Statistics
Modified Release
Patient-Centric Drug Development , Product Design, and Manufacturing
Pharmaceutical Impurities
QbD and Product Performance
Sterile Products
MSE—Manufacturing Science and Engineering section
Opportunities for students: 5 Travel ships
2 Graduate student research achievement awards
Volunteer opportunities on various committees with in the section
Mentoring program
Ambassador Program
MSE newsletter
Networking
Discussions in AAPS Blog and Linkedin (https://www.linkedin.com/groups/AAPS-Manufacturing-Science-Engineering-MSE-3910244/about)
For more information visit: http://www.aaps.org/MSE/
PPBPRESENTER: SOPHIA FONG, UNIVERSITY OF SOUTHERN DENMARK
PPB Section—Physical Pharmacy and Biopharmaceutics
Vision: recognized as the premiere global organization for scientists involved in physicochemical and biopharmaceutic characterization and delivery of small molecules and biologics.
Leadership: Chair: Weiguo Dai (J&J)
Chair-Elect: Roy Haskell (BMS)
Vice Chair: Allen Templeton (Merck)
Secretary/Treasurer: Eric Munson (University of Kentucky)
Past-Chair: Tycho Heimbach (Novartis)
Student representative: Sophia Y.K. Fong (University of Southern Denmark)
Dissolution Profile
Biorelevant Solubility
Drug Substance/Formulation
Solubility, pKa, etc.amorphous/crystalline
Nanotech
Precipitation
Time
Caco-2 or MDCK Papp
GI transporter
Jmax, Km
Effective Permeability
In vitro-In vivo
Scaling
PBPK modelsFabs , F
GI physiology:↑ Stomach pH↑ Stomach emptying Time↓ Intestinal pH↑ GI blood flow
Solubility↑ Bile Salt↑ In vivo solubility↓ Precipitation Rate
Permeability:Inhibition of Efflux or Uptake Transporters
Disposition PK (CL, Vd)
Material science
(polymorphs, forms, salts), physical
stability and chemical stability
PPB Section—Physical Pharmacy and Biopharmaceuticsa Multidisciplinary Science
Nanotechnology
Oral Absorption
Preformulation
Targeted Drug Delivery and Prodrugs
PPB Section—Physical Pharmacy and Biopharmaceutics
Focus Groups
PPB Section—Physical Pharmacy and Biopharmaceutics
Distribution of membership of PPB Section
4.37%
95.63%
95.6%4.4%
Regular members
Student members
As of July 2014
0
20
40
60
80
Origins of PPB international student membership
6.1%
Nu
mb
er o
f P
PB
stu
den
t m
emb
ers
6.1%
43.3%
11.7%
32.8%
Opportunities for students: Awards/Travelships
PPB mentorship program Mentors from pharmaceutical industry, academia and regulatory bodies
PPB newsletter and eBlast
Student executive committee
Welcome student volunteers to join!
PPB Education Initiative Funding for student chapters to invite renowned PPB scientists for 1-2 days
event
International ($1,500), US ($1,000)
PPB Ambassador Program
encourage volunteers to visit local universities and utilize the presentation slide deck to introduce AAPS and PPB Section
For more information visit: http://www.aaps.org/PPB/
PPB Section—Physical Pharmacy and Biopharmaceutics
PPDMPRESENTER: NICOLE ZANE, UNIVERSITY OF NORTH CAROLINA
Vision: Dedicated to discovery, development, and manufacturing of pharmaceutical products & therapies with focuses on the biopharmaceutics, pharmacokinetics, pharmacodynamics, metabolism, and transport of new and existing drugs.
Leadership: Chair: Reina Bendayan
Chair-Elect: Pankaj Desai
Vice Chair: Maciej Zamek-Gliszcynski
Secretary/Treasurer: Shannon Dallas
Past- Chair: Douglas Sweet
Student Representatives:
Camille Alam (University of Toronto)
Hari Ananthula (University of Cincinnati)
PPDM- PharmacokineticsPharmacodynamics Drug Metabolism
PPDM- PharmacokineticsPharmacodynamics Drug Metabolism
Specific research interests: Transporters
Enzyme-mediated metabolism
Preclinical pharmacokinetics
Microdialysis
Translating preclinical to clinical
In vitro-in vivo extrapolation
Systems pharmacology
Focus GroupsPrimary Drug Metabolism
Drug Transport
Microdialysis
Cellular and Molecular Toxicology
Secondary
Animal Pharmaceutics and Techonology Bioanalytical Bioequivalence Biomarkers in Translation medicine Contract Research Organization (CRO) Dermatopharmaceutics Discovery Modeling and Simulation Drug Candidate Selection Non-clinical Dose Formulation and Analysis Ocular Drug Delivery & Disposition Oral Absorption Pharmaco-imaging Pharmacometrics Systems Pharmacology Targeted Drug Delivery and Prodrug
PPDM- PharmacokineticsPharmacodynamics Drug Metabolism
Opportunities
Moderator Program Students moderate workshops at the annul meeting and
national biotechnology conference
PPDM Education Initiative Funds student chapters to invite prominent PPDM scientists to
travel to the chapter and teach about their research
Newsletter Students encouraged to submit news and stories that are
distributed bi-annually to all members
For more information visit: http://www.aaps.org/PPDM/
PPDM- PharmacokineticsPharmacodynamics Drug Metabolism
RSPRESENTER: ANQI WAN, UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES
RS—Regulatory Sciences sectionVision: To provide an international forum for advancing regulatory sciences by proactively fostering the development and realization of innovative, science-based regulatory solutions, which ensure the safety and efficacy of drugs, biologics, devices, and combination products.
Leadership:
Chair: Nagesh Bandi, Ph.D (Pfizer)
Chair-Elect: Monica Le Whitmire, MS
Vice Chair: Lynn C.Gold, Ph.D.
Secretary/Treasurer: Edward A. Narke
Past-Chair: Thirunellai G Venkateshwaran, Ph.D.
Student representative: Anqi Wan (University of Arkansas for
Medical Sciences)
RS—Regulatory Sciences section
Defining features:
Unique environment exhibiting characteristics similar to both academia and industry.
Protect public health by ensuring the safety and efficacy of drugs.
Provide public with accurate, science-based information on medications.
Empowers individuals with outstanding opportunities to serve the public as members of a world-class, science-based Public Health Agency.
RS—Regulatory Sciences section
Focus Groups
Bioequivalence Chemistry, Manufacturing and Controls
(CMC) CMC statistics Generic Pharmaceuticals
RS—Regulatory Sciences section
Opportunities for students:
Awards/Travelships
Networking opportunities
Mentoring program Mentors from pharmaceutical industry,
academia and regulatory bodies
RS newsletter
For more information visit: http://www.aaps.org/RS/
AAPS Student/Postdoc Outreach Development Committee (SPOD)Advocates and addresses issues of concern for students and postdoctoral fellows in the pharmaceutical and related sciences; Provides program funding Visiting Scientist Program Professional Development opportunities K – 12 STEAM outreach
SPOD Student Representatives: Vibhuti Agrahari (UMKC) Katie Maass (MIT)
For more information visit here.
Questions?
For more information about AAPS, visit: www.aaps.org
Or email Mary Jo Bean at BeanM@aaps.org
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