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IMMUNOTOXICOLOGY
Specialty Section
1 Immunotoxicology Specialty Section
2019-2020
Executive Committee
President
Emanuela Corsini
Vice President
Mark Collinge
Vice President-Elect
Florence G. Burleson
Secretary/Treasurer
Randle M. Gallucci
Past President
Jamie DeWitt
Senior Councilor
Jennifer Wheeler
Junior Councilor
Allison Ehrlich
Postdoc Representative
Alessandro Venosa
Student Representative
Alexa Murray
The Immunotoxicology Specialty Section
(ITSS) Newsletter is published twice a year
(Summer and Winter). If you would like to
share an item of interest with members of
the ITSS, please send it to the
Communications Committee Chair. All
comments and suggestions are welcome.
Alessandro Venosa
avenosa@pennmedicine.upenn.edu
Alexa Murray
alexa.murray18@gmail.com
Allison Ehrlich
ehrlicha@oregonstate.edu
Summer Edition
Incoming President’s Message 1
Outgoing President’s Message 4
ITSS Program at SOT 5
ITSS Committees 6
Student Post-doctoral Report 7
2019 Award Winners 8
Member Spotlight 12
Endowment Fund Update 14
Recent Immunotoxicology Publications 15
Immunotoxicology Membership Achievements and Awards 17
Save the date 18
Job Postings (from SOT Job Bank) 19
February 2019
Incoming President’s Message
Greetings fellow Immunotoxicologists! Time flies, already two years
passed since I was elected, and I am now the incoming ITSS
president for the 2019-2020 term, what an honor to serve. It seems
not long ago that I joined SOT and ITSS…it was 1992 so technically a
long time ago, since then I think I missed only 2-3 SOT annual
meetings. For those members that are less familiar with me, my
career in Immunotoxicology began under the mentorship of Drs. Mike
I. Luster and Gary Rosenthal at the NIEHS, where I spent two and half
wonderful years. Since then, I have been working in the Laboratory of
Toxicology, directed by Prof. Corrado Galli, in charge of the
Immunotoxicology and Immunopharmacology Unit, at the School of
Pharmacy of the University of Milan, Italy. As full professor in
toxicology, I am active in training undergraduate and graduate
students and in research. Currently, my research focuses on the
refinement of alternative in vitro tests for immunotoxicity, and on the
understanding at the molecular level the mechanism of action of
immunotoxic/immunomodulatory compounds. I am active in several
scientific and professional organizations, and I serve on several
editorial boards of toxicology journals. Regarding my experiences in
scientific societies, from 1999-2005 I served as Treasure for the Italian
Association for in vitro Toxicology; from 2009-2013 I was Member of
EUROTOX Education Sub Committee, from 2005-2011 I was the
Chair of the Immunotoxicology and Chemical Specialty Section at
EUROTOX; from 2010-2016 I was member of the IUTOX Executive
Committee; from 2017-2019 member of the Award Committee at SOT;
and from 2013 I am member of the EUROTOX Executive Committee.
President’s Message (Continued)
I think this is enough about me. I must sincerely thank the last year’s ITSS Executive Committee
and the leadership provided by Dr. Jamie Dewitt, outgoing ITSS President, and I am sure you all
remember her energy and organizational skills at the last SOT in Baltimore. A real great group to
work with, and Jamie, you know, you are not getting away that easy, we still have monthly
teleconferences and continue in our purposes.
I would also like to welcome the new members to the Executive Committee, Dr. Florence
Burleson (Vice President-Elect), Burleson Research Tehnologies, Inc.; Dr. Randy Gallucci
(Secretary/Treasurer), University of Oklahoma Health Sciences Center; and Dr. Allison Ehrlich
(Junior Councilor), Oregon State University.
The ITSS Executive Committee also sends thanks to the subcommittees and their volunteers,
including Education, Membership, Awards, and Program. Thanks for all the hard work!
The 2019-2020 year will be busy for the ITSS Executive Committee as usual. We want to build off
the successes from last year and continue to improve the visibility of our specialty section and its
impact within toxicology and within the SOT annual meeting.
In line with previous years, I would like to take an opportunity to highlight the main goals for ITSS
for the coming year.
Goal 1: Identify and/or create educational opportunities for ITSS membership. We will
continue to advertise all training opportunities for graduate students and postdocs as well as
continuing education, and mentoring event at SOT annual meeting. The ITSS Education
Committee will work hard to identify educational opportunities and translate them to the
membership. All ITSS members are welcome to contribute: if you find a course or webinar or other
training tool, please bring this to the attention of the ITSS Executive Committee [email to Mark
Collinge (Mark.Collinge@pfizer.com) and Jamie (DEWITTJ@ecu.edu)], Education Chair Florence
Burlenson (fburleson@brt-labs.com) or Emanuela Corsini (emanuela.corsini@unimi.it) so that we
can help spread the word.
February 2019 2 Immunotoxicology Specialty Section
Goal 2: Foster International Scientific Exchange and
Collaboration. The ITSS has a long- standing relationship
with the Japanese Society of Immunotoxicology (JSIT). This
partnership was established in 2005 to provide a vehicle for
exchange of science and education on an international level.
This program has been extremely successful and has led to
cutting-edge scientific presentations given by ITSS members
at the JSIT meeting and reciprocal presentation of cutting-
edge science by JSIT members
at the SOT meeting. We are proud to continue this relationship and to expand the
communication between ITSS and JSIT. This year Jamie Bonner from NC State University will
be our representative at the annual meeting of the JSIT. Reciprocal publications in respective
newsletters is now an ongoing strategy to share ideas and accomplishments throughout the
year. Building on the success of the ITSS-JSIT collaboration, the ITSS Executive Committee is
also expanding outreach to the Immunotoxicology and Chemical Allergy Specialty Section at
EUROTOX. A joint symposium has been proposed for SOT2020. Fingers crossed!
President’s Message (Continued)
Goal 4: Continue to involve the ITSS Past Presidents in the ITSS activities. The Science Advisory
subcommittee has been formalized under ITSS and will be tasked with reaching out to the Past
Presidents and engaging them in scientific discussions that will benefit the membership. One
excellent opportunity that comes to mind is a discussion about future hot topics and creating seeds
for program proposals. This will help foster the science that ITSS wants to represent at future
meeting. Past Presidents, be ready, keep an open mind, and let’s see where this can take us in our
pursuit of everything that is Immunotoxicology.
On behalf of the 2019-2020 ITSS Executive Committee, we look forward to working for the
membership for the coming year. We welcome and encourage any and all interactions with ITSS
members with the goal of making the specialty section inviting, productive, and visible.
We look forward to seeing you next year in Anaheim, CA!
As usual, if you have any questions, concerns, or suggestions, please feel free to reach out
to any member of the ITSS Executive Committee.
Best regards,
Emanuela Corsini, PhD
Universita’ degli Studi di Milano
President ITSS
February 2019 3 Immunotoxicology Specialty Section
Goal 3: Solidification of Endowment Fund. I will speak for the entire ITSS membership in
thanking Drs. Prakesh and Mitzi Nagarkatti for their gracious donation that established a new ITSS
Endowment Fund, now known as the “Mitzi and Prakash Nagarkatti Research Excellence in
Immunotoxicology Award Fund”. This fund is designed to encourage and recognize graduate
students and postdoctoral scholars for their excellence in research involving mechanisms of
immunomodulation in health and disease. The fund will provide travel awards for graduate
students and postdoctoral scholars to attend the SOT meeting providing them the opportunity to
present their research, gain valuable feedback from peers, learn cutting-edge science, and build a
network. In order to make this endowment fund permanent and receive matching funds from SOT
(this year will be the last year for SOT matching as SOT decided to shut down the program), ITSS
needs to raise only $1,150 to bring the fund to $25,000 and make it permanent.
SOT has made it easy for members to contribute to
the endowment. Please follow this link
(https://www.toxicology.org/endowment/ifc/fundC
ontributors.asp) and scroll to find the “Mitzi and
Prakash Nagarkatti Research Excellence in
Immunotoxicology Award Fund”.
Any and all contributions are welcome and greatly appreciated. We are almost there to
make it permanent!!!
Outgoing President’s Message
July 2019 4 Immunotoxicology Specialty Section
When we are in the midst of activities for a year, it seems like the year will never end. When that year is over, we stare in amazement at the calendar and how rapidly all of those days flew by. However, it’s usually a good idea to take stock of whether or not those activities resulted in meaningful outcomes. What did the ITSS accomplish in 2018-2019? It was my honor to serve as the ITSS President during this year and to work with a truly outstanding Executive Committee. The work of an organization is almost never done by one individual, but by a team of individuals concentrating on shared vision, goals, and objectives. As I look back through the Executive Committee teleconference agendas and subsequent minutes from the year, I see ambitious plans for ITSS that were carried out with enthusiasm and dedication. We updated mission statements for several of the committees, went live with a redesigned ITSS web site (largely due to the efforts of the 2017-2018 Executive Committee), supported international collaboration with the JSIT, and watched your donations help to grow the two endowment funds that support student and postdoc travel to the annual SOT meeting. We also endorsed nearly a dozen proposals for the annual SOT meeting, selected recipients for ITSS awards, and organized the reception that you all enjoyed at the annual SOT meeting. Of course, other tasks involved with the functioning of the specialty section were undertaken over the year as well. I encourage you all to stay active within the ITSS. Join a committee if you haven’t already done so (the awards committee will need members as the nominations start to roll in at the end of the year/early part of 2020). Run for an Executive Committee position! Elections take place at the end of the calendar year but it’s never too early to let our current president (Dr. Emanuela Corsini) know that you want your name on the slate for a particular position. At the very least, attend sessions endorsed by the ITSS, visit posters that focus on immunotoxicology, and enjoy catching up with colleagues at the annual meeting reception. The ITSS is a great specialty section because of the comradery of its members! I look forward to serving the 2019-2020 Executive Committee as Past-President and know that the current officers will guide the ITSS through this next year with typical enthusiasm and dedication! Dr. Jamie DeWitt President, ITSS 2018-2019 Past-President, ITSS 2019-2020
Enjoying a recent trip to Switzerland to talk about per- and polyfluoroalkyl substances (PFAS)!
ITSS Programs at SOT 2019
There are so many options to consider in addition to the above mentioned CE courses, symposia
and workshops. The latter is now available in two flavors: the canonical 165 minute session and
90 minute sessions. The latter would also allow for a 30-minute break before the following
session that can be used to promote interactions between attendees or follow ups with speakers.
Programming Committee is here to help!
Here is some useful advice to get you started: •The session presentations should be designed to provide a cohesive thread throughout the session.
•The session should address a topical issue of broad general relevance, rather than a narrow topic of
high interest to fewer scientists.
•The session presenters should reflect a diversity of opinions/backgrounds to reflect perspectives
from industry/regulators/academics.
•CE courses have a better chance of acceptance, as do roundtables – think about these formats as
a possibility.
Don't miss the opportunity to contribute to a program by submitting your scientific
proposal! Thank you in advance for your continuous support and contribution. We look
forward to receiving your proposal!
5 Immunotoxicology Specialty Section
Program Committee
Chair 2019-2020: Mark Collinge
Chair 2020-2021: Florence Burleson
It’s never too early to start planning
Dear ITSS members,
Let me start by thanking you all for your attendance to the ITSS-sponsored 2019
symposia!
In Baltimore, ITSS sponsored two continuing education courses on “Mechanistic
Understanding and Quantitative Risk Assessment in Immunotoxicology.” and ‘Microbiome and
Environmental Toxicants: From Study Design and Analysis to Regulatory Guidance’, two
symposia on “Immune-Epithelial Cell Crosstalk in Lung Toxicology and Disease” and “The
Current Application, Limitations, and Recent Advances in Humanized Mouse Models for
Evaluations of Immune Function and Preclinical Immunotoxicology Studies “, and one
workshop on “Understanding the Impact on the Immune System of Occupationally Relevant
Exposures to Multiwalled Carbon Nanotubes”.
The submission period for SOT
2020 is past but it is never too early
to think about 2021!! Your active participation within the Specialty
Section is vital for the section itself.
We know that the process of putting together a proposal may feel daunting, especially for
trainees. However, the ITSS program committee is here to help you submit the most competitive
proposal possible.
July 2019
ITSS Committees
6 Immunotoxicology Specialty Section July 2019
Education Committee
Mark Collinge Cody Smith
Jiajun (Brian) Zhou Travis Gulledge
Programming and Scientific Advisory
Committee
Vic Johnson Berran Yucesoy
Amira Mohammed Peer Karmaus
Ankit Shah Joanna Matheson
Awards Committee
Jennifer Wheeler Tina Satterwhite Wendy Freebern
Amira Mohammed Berran Yucesoy
Jean Sathish Wurood Neamah David McMillan
Yining Jin Joanna Matheson Anthony Franchini Michael McCabe
Michael Whitekas
Communications and Membership Committee
Allison Ehrlich
Alessandro Venosa Alexa Murray
Hasan Alghetaa Jiajun (brian) Zhou
Volunteers are always welcome:
SOT membership is required. Must be willing to become a member of the ITSS and to
commit to service. Please see the Committees page of the ITSS website for details.
Dear graduate students and postdocs,
It is an exciting summer ahead of us! We’re already in July! We watched fireworks and
celebrated, spent some time with family, and soon enough (too soon if you ask me) we’ll
start worrying about the next academic year.
Here are some quick updates from the past SOT meeting in Baltimore:
1. First and foremost, Baltimore's weather was much more clement this year, and that
already felt like a win! It was a great meeting and we are happy to say that the ITSS
sponsored symposia/workshop/CE courses were a great success!
2. We hosted the 5th ITSS mentoring event. We had 15 trainees attending and a remarkable
attendance from mentors (10) from academia, industry and government. We received
positive feedback about the format, speed dating-like rotation of the trainees. For next
year, based on your comments, we will reduce the timed component and provide some
time at the end of the event to have informal conversation with mentors you want to follow
up with. We keep striving to improve and make each event the best it can be!
3. We are working on CE courses and additional symposia for next year’s SOT meeting. We
will provide more information as we get closer to the meeting. If you missed out on the
opportunity to submit your proposals for 2020, do not worry! It is never too early to start
planning for 2021. If you need help getting started, the ITSS programming committee is
here to help! We’ll work together to tailor your ideas to their full potential.
4. Lastly, ITSS will be looking for a new postdoctoral representative, with the position
starting May 2020. If you are interested please contact me (avenosa1985@gmail.com)
or Alexa (alexa.murray18@gmail.com) ! In addition, we also encourage the ITSS trainee
members to participate in any other ITSS committee. This is a great way to get involved in
leadership activities with other ITSS members and to enhance your professional network.
There are 4 different committees within ITSS: Awards, Program, Education and
Communication/Membership.
Keep up with the great science and see you in 2020!
Student & Postdoctoral Report
7 Immunotoxicology Specialty Section
Alessandro Venosa, Pharm.D., Ph.D. and Alexa Murray, Ph.D. Candidate
July 2019
Outstanding Senior Investigator Award
The Vos Award for Lifetime Career Achievement in Immunotoxicology is presented to an
individual in recognition of career achievements in advancing the field of immunotoxicology
through service, leadership, and scientific contributions.
The Outstanding Senior Investigator Award is presented to an individual whose work has made
significant contributions to the field of Immunotoxicology. This award is for scientists in
academia, industry, or those who have had an impact on regulatory issues, and has
distinguished themselves as leaders in their chosen area of immunotoxicology.
2019 ITSS Award Winners:
Vos Award for Lifetime Career Achievement in Immunotoxicology
Dr. Frank Gerberick Adjunct Appointment in Innovations in Food & Chemical Safety (IFCS) Programme at A*STAR
Dr. Raymond H.H. Pieters
Immunotoxicology, Institute for Risk
Assessment Sciences, Utrecht
University, The Netherlands
8 Immunotoxicology Specialty Section July 2019
Outstanding Young Investigator Award
The Outstanding Young Investigator Award is presented to an individual whose work has made
significant contributions to the field of Immunotoxicology. This award is for scientists in
academia, industry, or those who have had an impact on regulatory issues, having 10 years or
less of experience since obtaining their highest degree.
Dr. Jonathan Shannahan
Assistant Professor of Health Sciences and
Toxicology
Purdue University
Mitzi and Prakash Nagarkatti
Research Excellence in
Immunotoxicology Student
Award
Brian Zhou
Michigan State University
Mitzi and Prakash Nagarkatti
Research Excellence in
Immunotoxicology Award
Dr. Hui Wang
Michigan State University
9 Immunotoxicology Specialty Section July 2019
2019 ITSS Award Winners:
Best Paper of the Year 2018
Heedoo Lee1, Duo Zhang1, Debra
Laskin2, and Yang Jin1 1Division of Pulmonary and Critical Care Medicine,
Boston University 2Department of Pharmacology and Toxicology,
Rutgers University
Functional evidence of pulmonary
extracellular vesicles in infectious and
noninfectious lung inflammation
10 Immunotoxicology Specialty Section July 2019
2019 ITSS Award Winners:
Health and Environmental Sciences Institute (HESI)
Immunotoxicology Young Investigator Travel Award
Dr. Yining Jing
Michigan State University
Best Presentation by a Student Award
Robert Freeborn
Michigan State University
11 Immunotoxicology Specialty Section July 2019
Best Presentation by a Postdoctoral Trainee Award
Dr. Lance K. Blevins
Michigan State University
Identification and characterization of a
sensitive immunologic target of TCDD:
CD5+ innate-like B cells
2019 ITSS Award Winners:
Member Spotlight
Cheryl Rockwell, Ph.D.,
Associate Professor, Pharmacology & Toxicology
Michigan State University
• When did you begin your career in immunotoxicology?
In 2000, when I started my dissertation research in
Dr. Norb Kaminski’s lab.
• When did you start participating in the ITSS?
I became a member of ITSS as a graduate student. At first,
I simply attended the ITSS reception, but gradually started
becoming active in committee work.
• What motivated you to be a part of ITSS?
Really there are a lot of benefits. It is a great way to network and meet people as a
trainee. I also felt like I wanted to give back to ITSS because it is very supportive of
trainees. Also, I enjoy working on ITSS committees 😊
• What was your most rewarding experience involving ITSS?
There have been many, but probably initiating the first couple of
Mentoring/Networking events with Ashwini Phadnis was the most rewarding. I have
also enjoyed serving on the Awards committee and as Councilor to ITSS.
• How did you make the transition to independence? Any advice for the
trainees out there?
It takes some patience and a plan. You have to be deliberate in how you will
eventually make that leap. You also need to be able to adjust your plan as you go
along. Hard work is critical. If I were to identify a crucial mistake that I made early
on, it would be that I did not initially get enough feedback from multiple perspectives
on those first couple of fellowship applications.
• What element of your training had the largest impact on your personal and
scientific growth?
It is hard to identify a single element. However, in retrospect, I think learned more
and grew as a scientist during those times when I felt like I was failing rather than
when everything was going well. The times when nothing was working in the lab
forced me to improvise and grow new troubleshooting muscles. Even receiving
crushing rejections of grants and manuscripts pushed my development forward at
times I think.
12 Immunotoxicology Specialty Section July 2019
Member Spotlight (Continued)
• What experiences best prepared you for your job?
There have been so many. Dr. Norb Kaminski taught me the fundamentals of
becoming an effective researcher and grant writer. I gained a lot of independence
and confidence during my first postdoc in Dr. Nilo Qureshi’s lab—I also learned a lot
more about grant-writing from Dr. David Morrison at that time. My current scientific
interests were ignited during my second post-doc in Dr. Curt Klaassen’s lab. All of
these experiences have shaped me into the scientist I am today.
• How does the future look in the immunotoxicology field?
The future is unquestionably bright from the perspective that there are more jobs and
opportunities in our area than ever before. There are new challenges for us to
tackle—I believe these challenges will keep us all very busy for many, many years to
come.
• What would you do (or currently do) to improve industry-academia
interactions?
I agree that we need to work together more. I am not sure how to accomplish this on
the industry side, however I have lots of ideas for the academic side. Many of our
academic institutions have a fair amount of bureaucracy—this can impact the speed
of research. We need to figure out a system that accomplishes the goals and needs
of the universities without sacrificing large amounts of time and resources on the side
of the scientists who wish to collaborate. I think the slow speed of universities is a
deterrent to collaboration.
• What has been the largest benefit, for you, of being an active participant in
an SOT SS like the ITSS?
SOT is a unique scientific society in that it solicits and relies heavily on volunteer
activities from its membership. I love this aspect of our society. It provides so many
opportunities to be engaged. SOT members have the opportunity to shape the
scientific programs and many other aspects of the society. SOT is also unique in that
its membership is split among academia, industry and regulatory institutions—this is
a strength. I think SOT could serve as a model for other scientific societies in these
ways.
• What is one fun fact about yourself that you would like to share with others?
Hmmm—that is a toughie. With a 6-year-old and a 2-year-old at home, I have
become somewhat no-nonsense these days. However, my 6-year-old and I have
recently become avid geocachers, which is a fairly addictive activity for people who
like exploring the outdoors.
13 Immunotoxicology Specialty Section July 2019
Endowment Fund Update
We wanted to take this opportunity to thank everyone who has contributed to the
Mitzi and Prakash Nagarkatti Research Excellence in Immunotoxicology
Award Fund. This fund was established to encourage graduate students and
postdoctoral scholars to pursue cutting-edge mechanistic research on
immunomodulation seen in health and disease and share that widely with the
research community.
The current amount of the endowment is $48,850 and we need to raise
$1,150 before January 2020 to make it permanent.
Keep in mind that SOT donation matching started July 1st 2019!!!
We thank you in advance for your generosity and look forward to making the
Nagarkatti Endowment a permanent part of the Immunotoxicology Specialty
Section!
Randle M. Gallucci
Secretary/Treasurer
14 Immunotoxicology Specialty Section
Use the online giving system or download the Donation form to make a
gift to the Mitzi and Prakash Nagarkatti Research Excellence in
Immunotoxicology Award Fund
July 2019
15 Immunotoxicology Specialty Section
Recent Publications Compiled by Alessandro Venosa and Alexa Murray. Anytime you have a new fully-
published or electronically available article to report, please send the citation to
Alessandro at avenosa@pennmedicine.upenn.edu.
Beamer CA, Kreitinger JM, Cole SL, Shepherd DM. Targeted deletion of the aryl hydrocarbon receptor
in dendritic cells prevents thymic atrophy in response to dioxin. Arch Toxicol. [Epub ahead of print]
Bechara R, Maillere B, Joseph D, Weaver RJ, Pallardy M. Identification and characterization of a naïve
CD8+ T-cell repertoire for benzylpenicillin. Clin Exp Allergy. 2019 Jan 18. doi: 10.1111/cea.13338. [Epub
ahead of print]
Buoso E, Ronfani M, Galasso M, Ventura D, Corsini E, Racchi M. Cortisol-induced SRSF3 expression
promotes GR splicing, RACK1 expression and breast cancer cells migration. Pharmacol Res. 2019
May;143:17-26. doi: 10.1016/j.phrs.2019.03.008. Epub 2019 Mar 9. PubMed PMID: 30862604.
Calhoun KN, Luckett-Chastain LR, Frempah B, Gallucci RM. Associations Between Immune Phenotype
and Inflammation in Murine Models of Irritant Contact Dermatitis. Toxicol Sci. 2019 Mar 1;168(1):179-
189. doi: 10.1093/toxsci/kfy289. PubMed PMID: 30517752.
Franchini, Anthony, Myers Jason, Jin Guang-Bi, Shepherd David, and Lawrence Paige. Genome-Wide
Transcriptional Analysis Reveals Novel AhR Targets That Regulate Dendritic Cell Function during
Influenza A Virus Infection. ImmunoHorizons June 1, 2019, 3 (6) 219-235; DOI:
https://doi.org/10.4049/immunohorizons.1900004
Frempah B, Luckett-Chastain LR, Gallucci RM. IL6Rα function in myeloid cells modulates the
inflammatory response during Irritant Contact Dermatitis. Exp Dermatol. 2019 Jun 5;. doi:
10.1111/exd.13984. [Epub ahead of print] PubMed PMID: 31165501.
Frempah B, Luckett-Chastain LR, Calhoun KN, Gallucci RM. Keratinocyte-specific deletion of the IL-
6RΑ exacerbates the inflammatory response during irritant contact dermatitis. Toxicology. 2019 May
31;423:123-131. doi: 10.1016/j.tox.2019.05.015. [Epub ahead of print] PubMed PMID: 31158415.
Holaskova, Ida, Meenal Elliott, Kathleen Brundage, Ewa Lukomska, Rosana Schafer and John B
Barnett. 2019. Long-term immunotoxic effects of oral prenatal and neonatal atrazine exposure. Toxicol
Sciences. (ahead of print) doi: 10.1093/toxsci/kfz005
Katzen J, Wagner BD, Venosa A, Kopp M, Tomer Y, Russo SJ, Headen AC, Basil MC, Stark JM,
Mulugeta S, Deterding RR, and Beers MF. A SFTPC BRICHOS Mutant Links Epithelial ER Stress and
Spontaneous Lung Fibrosis. Journal of Clinical Investigation Insight. 2019;4(6):e126125.
Kavasi RM, Berdiaki A, Spyridaki I, Papoutsidakis A, Corsini E, Tsatsakis A, Tzanakakis G, Dragana N.
Contact allergen (PPD and DNCB)-induced keratinocyte sensitization is partly mediated through a low
molecular weight hyaluronan LMWHA)/TLR4/NF-κB signaling axis. Toxicol Appl Pharmacol. 2019 Jun
18:114632. doi: 10.1016/j.taap.2019.114632. [Epub ahead of print] PubMed PMID: 31226360.
Ishihara Y, Haarmann-Stemmann T, Kado NY, Vogel CFA. Interleukin 33 expression induced by aryl
hydrocarbon receptor in macrophages. Toxicol Sci. 2019 May 15.pii: kfz114. doi: 10.1093/toxsci/kfz114.
July 2019
Recent Publications (Continued)
Ishihara Y, Kado SY, Hoeper C, Harel S, Vogel CFA. Role of NF-kB RelB in Aryl Hydrocarbon Receptor-
Mediated Ligand Specific Effects. Int J Mol Sci. 2019 May 30;20(11). pii: E2652. doi:
10.3390/ijms20112652
Impinen A, Longnecker MP, Nygaard UC, London SJ, Ferguson KK, Haug LS, Granum B. Maternal
levels of perfluoroalkyl substances (PFASs) during pregnancy and childhood allergy and asthma related
outcomes and infections in the Norwegian Mother and Child (MoBa) cohort. Environ Int. 2019 Jan
23;124:462-472.
Satoh R, Tsuge I, Tokuda R, Teshima R. Analysis of the distribution of rice allergens in brown rice grains
and of the allergenicity of products containing rice bran. Food Chem. 2019 Mar 15;276:761-767.
Tsuji M, Koriyama C, Ishihara Y, Vogel CFA, Kawamoto T. Association between bisphenol A diglycidyl
ether-specific IgG in serum and food sensitization in young children. Eur J Med Res. 2018 Dec
26;23(1):61.
Venosa A, Katzen J, Tomer Y, Kopp M, Jamil S, Russo SJ, Mulugeta S, and Beers MF. Epithelial
Expression of an Interstitial Lung Disease Associated Mutation in Surfactant Protein-C Modulates
Recruitment and Activation of Key Myeloid Cell Populations in Mice. Journal of Immunology, 2019. 202
(9) 2760-2771
Vogel CFA, Ishihara Y, Campbell CE, Kado SY, Nguyen-Chi A, Sweeney C, Pollet M, Haarmann-
Stemmann T, Tuscano JM. A Protective Role of Aryl Hydrocarbon Receptor Repressor in Inflammation
and Tumor Growth. Cancers (Basel). 2019 Apr 27;11(5).
Yang Z, Zhao Y, Li Q, Shao Y, Yu X, Cong W, Jia X, Qu W, Cheng L, Xue P, Zhou Z, He M, Zhang Y.
Developmental exposure to mercury chloride impairs social behavior in male offspring dependent on
genetic background and maternal autoimmune environment. Toxicol Appl Pharmacol. 2019 May
1;370:1-13. doi: 10.1016/j.taap.2019.03.006. Epub 2019 Mar 9.
16 Immunotoxicology Specialty Section July 2019
Achievements and Awards
Danuta Herzyk, PhD (past ITSS President)
Sr Scientific Director at Merck Pharmaceuticals SOT Scientific Program Committee
17 Immunotoxicology Specialty Section July 2019
Cheryl Rockwell, PhD
Associate Professor
Department of Pharmacology & Toxicology
Michigan State University
2019 Early Career Award ASPET Toxicology Division
Alessandro Venosa, PharmD, PhD
Postdoctoral Researcher
University of Pennsylvania School of Medicine
2019 Usha Awards APS, Respiratory Section
A symposium to recognize the career of
Dr. Nancy Kerkvliet
member in the College of Veterinary Medicine at Oregon State University in 1976 and
joined the Department of Environmental and Molecular Toxicology in 1995.
During this time she has mentored many graduate students and postdoctoral fellows that
have gone on to successful scientific careers. For her excellence in mentoring she was
presented with the Women in Toxicology Mentoring Award in 2014. Dr. Kerkvliet has
served the scientific community as President of the Society of Toxicology
Immunotoxicology Specialty Section, the President of the Pacific Northwest Association of
Toxicology (PANWAT) and received the PANWAT Achievement Award in 2011. Dr.
Kerkvliet’s scientific career evolved in concert with the evolving field of immunotoxicology.
During most of this time, she has been focused on trying to understand the mechanisms
of aryl hydrocarbon receptor (AHR)-mediated immunomodulation. Until recently, most of
her work was focused on 2,3,7,8 tetrachlorodibenzo-p-dioxin (TCDD), the most potent
AHR ligand and notorious as a toxic environmental contaminant. Her laboratory was the
first to describe the potent suppression of T cell dependent immune responses by TCDD
and investigated the cellular basis for the suppression, describing AHR-driven changes in
T cells and dendritic cells. Dr. Kerkvliet was also first to identify the ability of AHR
activation to induce regulatory T cells. AHR regulation of T cell differentiation is now the
subject of research in laboratories around the world. This event organized by Kerkvliet’s
former trainees and colleagues represents a celebration and demonstration of their
appreciation for her efforts over the past half-century. Please join us in beautiful Corvallis!
Here is a link to the meeting web site:
https://emt.oregonstate.edu/kerkvlietsymposium/kerkvlietsymposium.
You can register even if you cannot attend – There is a portal for everyone to write a
personal message – sharing memoires, stories, and pictures for Nancy that we will collate
in a bound book.
Oregon State University, Corvallis, OR
Friday September 13, 2019 | 8:30-4:00 PM
This event organized by Dr. Kerkvliet’s former trainees and colleagues represents a celebration and demonstration of their
appreciation for her collective efforts over the past half-century.
Save the date
18 Immunotoxicology Specialty Section July 2019
We are pleased to announce a Career Recognition
Symposium and Celebration honoring the career of Professor
Nancy Kerkvliet to take place on the Oregon State University
Campus on September 13th, 2019. Dr. Kerkvliet received her
BS degree (1970) from University of Wisconsin-Eau Claire and
her MS (1973) and PhD (1976) in Interdisciplinary Biological
Sciences at Oregon State University. She became a faculty
Job Postings (from SOT Job Bank)
19 Immunotoxicology Specialty Section
Organization Location Job Title
AbbVie North Chicago, IL
United States Occupational Toxicologist
AbbVie North Chicago, IL
United States Senior Scientist II/III, Toxicology
ANGUS Chemical Company Buffalo Grove, IL
United States North & South America Product Steward
Apple Cupertino, CA
United States
Senior Toxicologist / Senior Biocompatibility
Engineer
Arylessence Marietta, GA
United States Regulatory Affairs Manager
Bill & Melinda Gates Research
Institute
Cambridge, MA
United States Discovery Project Leader- Toxicology
BioMarin Pharmaceutical San Rafael , CA
United States
Scientist 2: PreClinical Pharmacology /
Toxicology, Pharmacological Sciences
California Environmental
Protection Agency
Sacramento, CA
United States Deputy Director of Scientific Programs
ChemoCentryx Mountain View, California
United States Director of Toxicology
Cornell University Ithaca, NY
United States
Postdoctoral Associate_Molecular and
Neuroendocrine Toxicology
Covance Madison, WI
United States
Associate Director/ Scientific Lead – PK
Modeling & Simulation
Covance Madison, WI
United States Pharmacokineticist Associate
CropLife America Washington, DC
United States Director, Science Policy
Dechra Portland , Maine
United States
Product Development Manager, Global Drug
Safety
Department of Pesticide
Regulation, California EPA
Sacramento, California
United States Epidemiologist/Biostatistician
Department of Pesticide
Regulation, California EPA
Sacramento, California
United States Dermal Toxicologist
Eastman Chemical Company Kingpsort, TN
United States
Lead, Toxicology and Regulatory Assesment
Services
Environmental Protection
Agency
Washington, DC
United States
Biologist/Toxicologist/Physical
Scientist/Chemist
EPA Washington, DC
United States Biologist/Toxicologist
EPA Washington, DC
United States Biologist/Toxicologist
EPA Washington, DC
United States Biologist/Toxicologist
FDA Silver Spring, MD
United States Post-doctoral Fellow
July 2019
Job Postings (from SOT Job Bank)
20 Immunotoxicology Specialty Section
Organization Location Job Title
Florida International University Miami, Florida
United States
Tenure-Track Assistant Professor -
Department of Environmental Health Sciences
Food & Drug Administration Silver Spring, Maryland
United States
Post-doctoral fellow position: Assess the
applicability of alternatives to animal testing for
detection of potential allergens in medical
devices
Fresenius Medical Care Waltham, MA
United States Senior Toxicologist
Genentech
South San Francisco,
California
United States
Study Operations Manager
Givaudan Singapore Senior Manager Regulatory Affairs & Product
Safety (Toxicology) in Singapore
Givaudan France Manager, Toxicology – Regulatory and
Product Safety (RAPS)
Gossamer Bio San Diego, CA
United States Senior Scientist, Toxicology
Institute for In Vitro Sciences Gaithersburg, Maryland
United States Toxicologist - I
Institute for In Vitro Sciences Gaithersburg, Maryland
United States
Post-doctoral Scientist – Respiratory
Toxicology & Immunology
Institute for In Vitro Sciences Gaithersburg, Maryland
United States Toxicologist II - Respiratory
International Flavors &
Fragrances
Union Beach, New Jersey
United States Food and Flavoring Toxicologist
Mary Kay Inc. Lewisville, TX
United States Senior Scientist Product Safety
Medpace Cincinnati, Ohio
United States
Nonclinical Drug Development Strategist -
Pharmacology, Pharmacokinetics, Toxicology
Michigan State University United States Postdoctoral Position in Immunotoxicology
Michigan State University United States Postdoctoral Position in Immunopharmacology
Michigan State University East Lansing, MI
United States Post-Doctoral Research Associate
National Institute for
Occupational Safety and Health
Cincinnati, OH
United States Toxicologist/Risk Assessor
National Institute of
Environmental Health Sciences
RTP, NC
United States
Editor-in-Chief, Environmental Health
Perspectives
Nestlé Lausanne,
Switzerland Senior Food Safety and Toxicology Scientist
NJ Dept. of Env. Protection Trenton, NJ
United States Research Scientist 2 - Toxicologist
Novartis Cambridge, MD
United States
Safety Assessment Expert, Preclinical Safety
(PCS)
July 2019
Job Postings (from SOT Job Bank)
21 Immunotoxicology Specialty Section
Organization Location Job Title
Novartis Pharma AG Cambridge, MA
United States
Senior Investigator, Cell and Gene Therapy
Expert
Pacific Northwest National
Laboratory
Richland, WA
United States Exposure Science in Genetics
Pacific Northwest National
Laboratory
Richland, WA
United States Data Science and Bioinformatics
Pacific Northwest National
Laboratory
Richland, WA
United States
Human Exposure, Toxicology and Precision
Medicine
Regeneron Tarrytown, New York
United States Staff Scientist, Toxicology - 15571BR
Reynolds American Winston-Salem, NC
United States Systems Biologist - Biomarker Research
Rimkus United States Principal Toxicologist
Rimkus Consulting Group Houston, Texas
United States Toxicologist
Roche Innovation Center
Shanghai
Shanghai,
China Group Head PS-iSafe RICS,
SciLucent Herndon, VA
United States
Senior/Principal Regulatory Toxicology
Consultant
Silent Spring Institute Newton, MA
United States
Bioinformatics and Data Science for Public
Health
Stockholm University Stockholm, Sverige
Sweden
Postdoctoral Fellow in Molecular in vitro
Toxicology
The University of Arizona Tucson, AZ
United States
Full/Associate Professor in Environmental
Health Sciences
Toxics Use Reduction Institute,
UMass Lowell
Lowell, MA
United States TURI Science/EHS Support Specialist
University at Albany Rensselaer, New York
United States Assistant/Associate Professor
University of Alabama at
Birmingham
Birmingham, AL
United States
Assistant or Associate Professor -
Environmental Health Sciences
University of Minnesota Saint Paul, Minnesota
United States
Pharmacology/Toxicology in Food Animal
Production Assistant or Associate Professor
University of Rochester Rochester, NY
United States
Postdoctoral Positions in Inhalation
Toxicology
US Food and Drug
Administration
Silver Spring, MD
United States Research Toxicologist, Risk Assessor
US Food and Drug
Administration
Silver Spring, Maryland
United States
Post-doctoral Fellow Nanotechnology Organ-
on-a-Chip
WestChina-Frontier
PharmaTech
Chengdu, Sichuan
China
Veterinarian; Market Manager; Study Director
of Pharmacokinetics; Pathologist; Study
Director
Xerox Corporation Webster, New York
United States Regulatory Toxicologist
July 2019
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