IHT Corporate Presentation v9

CORPORATE PRESENTATION

IHT Group

Key dates

Hospital Care

Others business

Woundynamic

Quick facts Group Key �gures

About us

Our Mission

Objectives

Milestones

Business Units Cordynamic

ABOUT US

OBJECTIVESMILESTONES OUR MISSIONBUSINESS UNITS ABOUT US

IHT (Iberhospitex, S.A.) is a European company, based in Barcelona, with over 34 years’ experience in healthcare technologies (1980-2014). We market our products worldwide.

Our aim is to continue manufacturing high quality products, focusing particularly on Skin & Wound Care (Hospital Care Business Unit) and Less invasive treatment for cardiovascular disease (Cordynamic Business Unit).

In 1980 IHT was founded in Barcelona by its current president, Aniceto López. Together with IHT’s initial collaborators, he developed the brand’s �rst products: disposable surgical drapes and Drenofast.

In 1985 the company moved to Lliçà de Vall, a town located 30 km outside Barcelona. Today the majority of the group’s operations are carried out from this location.

During the second half of the 1980s IHT began to expand internationally, widening its network of sales of�ces and establishing a branch in France.

MadridSales & tenders of�ces

Lliçà de Vall, BarcelonaHeadquarters

Colomiers, ToulouseClinical IHT, French delegation

OUR MISSION

MILESTONESBUSINESSUNITS OBJECTIVESABOUT US OUR MISSION

To improve patients’ quality of life, while also meeting the needs of healthcare professionals.

OBJECTIVES

BUSINESS UNITSABOUT US MILESTONESOUR MISSION OBJECTIVES

Three driving forces:

· Internationalitzation · Investment in new business areas · Research

Looking ahead

MILESTONES

Key datesQuick facts Group key �gures

ABOUT USOUR MISSIONBUSINESS

UNITSOBJECTIVES MILESTONES

Drenofast: Over 3 million units/year

Opers - Woundynamic: Over 6 million units/year

Oper Cat (Exclusive products) Over 12 million units sold Innovative self-adhesive dressing pouch

Coronary Stents & Balloons: Over 42,000 units/year

Coronary Catheters (Exclusive products) Amicath®, the best perfusion catheter

ISO 13485 & 14001

Founded: 1980 in Barcelona

Ownership: Private

Figures: 4 Facilities

Logistics Size: Over 3,000m2

Manufacturing & Of�ces Size: Over 7,000 m2

Employees: Over 180

Operations: 52 countries

Revenue: Over €30 million

Aspirator: Over 1.5 million units/year

1985New facilites in

Lliçà de Vall

2003New logistics warehouse

and sterilisation plant opens in Montmeló

2011IHT Innovations created

due to the restructuring of the R&D Department

1990IHT Medical is created for the import and distribution of hospital products

1993IHT Clinical France

begins commercial operations in the French market

1998IHT Cordynamic starts to develop and market Interventional Cardiology devices

Company Key dates

1980IHT is founded by Aniceto Lopez in Barcelona with Hospital Care products

2010New manufacturing

facilities for Hospital Care products in Cantallops

6,000 m2

1982Drenofast

Redon drainage with incorporated vacuum

Oper �lm Transparent

self-adhesive polyurethane �lm

1986Oper tapeNon-woven self-adhesive roll

1987Oper dresNon-woven self-adhesive dressing with central pad

Products Key dates Woundynamic - Hospital Care

1980Surgical drapesSurgical drapes single use

2000Oper catSelf-adhesive dressing pouch for the protection of catheters

2013Oper dres �lmPolyurethane self-adhesive dressing with central pad

Oper stripAdhesive strip for cutaneous sutures

Oper plast strip & spotPolyethilene adhesive stripes

Oper tape paperNon-woven surgical tape

Oper tape clearTransparent plastic surgical tape

2014Oper cat “new”Self-adhesive dressing pouch for the protection of catheters

Oper �lm surgical Transparent self-adhesive polyurethane surgical �eld protector

Oper easy IV & IV strip Transparent self-adhesive IV polyurethane dressing (with or without strips)

Oper easy Transparent self-adhesive polyurethane dressing for �xation and protection

1990AspiratorDisposable system for the aspiration of body �uids

Products Key dates Cordynamic

2003BionertInert Bare metal stent

ApoloStainless Steel Bare metal stent

2004AmicathIntracoronary drug infusion catheter

2007ActivePaclitaxel drug eluting stent

2009IristSinvastatin drug eluting stent

2015Destiny

New generation drug eluting stent

2005AccesPTCA Guiding Catheter

2008HunterThrombus aspiration catheter for IAM

FairwayPTCA semicompliant balloon

2014Hunter ST Thrombus aspiration catheter for IAM with improved pushability

iChrom Inert CoCr Bare metal stent

CrosswayNew generation PTCA semicompliant balloon

Crossway NC New generation PTCA non compliant balloon

Group’s revenue over 30 million € (30% international activity)Over 180 employeesEstimated annual investment in R&D 8%Logistic facilities > 3,000 m2

Manufacturing and central of�ces > 7,000 m2

2004 2006 2008 2010 2012 2014 2016 2018

Evolution of IHT revenue since 2004 and projection to 2018

IHT Figures

R&D Department / R&D Investment annual turnover

BUSINESSUNITS

WoundynamicCordynamic Hospital Care Other business

OUR MISSIONOBJECTIVES ABOUT USMILESTONESBUSINESS

WoundynamicCordynamic Hospital Care Others business

Minimally invasive treatments for cardiovascular disease/pathology

Less invasive treatment for cardiovascular disease business unit

Coronary Technologies

Inertization

Stents

Catheters

Peripheral market is not included. Data source: American Journal of Cardiovascular Association.

Worldwide BMS & DES market

7,7 7,7

Others BMS DES

DES Coronary stents AMI devices

BMS Coronary stents Guide catheters

Balloons

Active

Destiny

Amicath

Hunter

Hunter ST

Bionert

iChrom

Access

Crossway

Crossway NC

Amicath®

Perfusion catheter in AMI

Amicath is a coronary catheter for an easier and safer primary angioplasty in AMI

Amicath offers multiple applications:

Intracoronary drug administration

· Prevention of NO re�ow phenomenon. · Improvement of distal microcirculation. · Thrombotic load disaggregation.

Rapid rechanneling of the occluded artery

Thrombotic load visual assessment

· Optimal assessment of the thrombotic load. · Visualization of the whole affected vessel (proximal and distal areas). · Measurement of damage for direct stenting.

Hunter®

Thrombus extractor

Ideal characteristics of a manual thrombus extractor

High aspiration capacity

Large internal extraction area.

Sliding internal surface.

Easy access to the area to treat

No kinking.

Good navigability

· Hydrophilic external surface. · No external friction with the guiding catheter.

Excellent pushability.

Main features

Apolo is a 316 L stainless steel stent.

Two speci�c designs: Apolo 3 and Apolo Small.

Due to its structure, composition, and design, it offers a great radial strength.

Thanks to its excellent �exibility and navigability properties, Apolo is an ideal metal stent to reach distal complex lesions in tortuous vessels.

Safety and ef�cacy

APOLO¹ and ASSET² study.

Apolo®

Bare metal stent

1. Serra A et al. Registro multicéntrico, prospectivo del stent APOLO. Resultados clínicos y angiográ�cos a los 6 meses.

2. Goicolea J et al. Apolo study on small vessels target. Estudio multicéntrico y prospectivo. Resultados clínicos y angiográ�cos a los 6 meses.

A new and safe alternative to restenosis

Biocompatible stent without external coating

· Inhibits thrombosis. · Reduces in�ammatory response. · Regulates neointimal hyperplasia.

Main features

Bionert is a 316 LVM stainless steel stent, with a modi�ed surface due to the implantation of oxygen ions, this making it a biologically inert material.

Due to its structure, composition, and design, it offers a great radial strength.

Thanks to its excellent �exibility and navigability properties, Bionert is an ideal metal stent to reach distal complex lesions in tortuous vessels.

Bionert®

Inert coronary stent

Irist, safety alternative to DES and greater ef�cacy than BMS

Patients with moderate risk of restenosis requiring a safe DES

· Patients under chronic anticoagulation. · Expected premature withdrawn of anti-platelet therapy. · Patients with high risk of bleeding. · Patients with known resistance to ASA and/or Clopidogrel.

Irist offers a moderate cell proliferation inhibition (moderate late loss) and a high safety pro�le based on reendothelization.

Irist®

Sinvastatin DES

Active and Active Small structure and components

P5, biocompatible polymer · Contains tri�usal. · Reduced platelet aggregation. · Good reendothelization. · Ef�cient drug release. · Safe mechanical properties.

Apolo 3 and Apolo Small platforms, a perfect functionality · Two speci�c designs. · Great radial strength. · Excellent navigability. · Good apposition.

Paclitaxel, demonstrated ef�cacy · Cytostatic agent. · Recognized clinical evidence. · Dosing and safe elution.

Active®

Paclitaxel DES

2014 - 2015 New Products

iChrome: CoCr Inert stent

Crossway NC CrosswayDestiny Hunter ST

iChrom®

Inert CoCr Coronary Stent

Main features

Excelent deliverability for very low pro�le and �exibility.

Second generation inertizacion technology for biocompatible metal surface.

Good appositioning with oustanding radial force.

Delivering a safer Stenting

· Innovative and safer stent technology. · Second generation stent inertization process. · Biocompatible metal surface. · Unique inert CoCr stent on the market. · Excelent deliverability with oustanding radial force.

HunterST®

Hydrophilic aspiration catheter

Ef�cacy goes beyond

· Improved pushability. · Maximum aspiration capacity. · Safer procedure due to higher distal visibility.

Improved pushability.

Internal metalic stylet.

Maximum aspiration capacity for big thrombus management.

The largest aspiration capacity.

Crossway®

PTCA Semicompliant Balloon

Leading the way

Achieving the right balance to meet the clinical need.

4º Generation IHT Cordynamic PTCA Balloon Catheter

· Push - Track - Cross. · Redesigned balloon. · New tip design. · Very low pro�le.

Powerful and Precision

· Guaranteed and safer high pressure post dilatation. · Outstading recrossability capacity. · Safe and acurate post dilatation. · 20 Atm rated burst pressure. · 4% Balloon growth rate.

Crossway®NCPTCA Non-Compliant Balloon

DestinyThe new DES generation is coming to IHT

Medical devices for health care

DrenofastRedon drain with incorporated vacuum

Drenofast is indicated for wound drainage and exudate and organic �uids removal

Perfection in drainage

· Incorporated vacuum. · Greater probe’s aspiration surface. · Reduced healing time. · Easy handling.

An ef�cient and safe drainage

Drenofast is a sterile Redon drain system intended for single use, with incorporated vacuum (low and medium vacuum pressure).

Various bottle sizes available (200, 400, 600 ml), and equipped with probe and CH6-CH18 needle.

AspiratorSurgical aspiration

Technical chart

Equipment Material

Bags PVC free

Container

Trolley

Flexible thermoplastic

Polyethilene

Polycarbonate

Chromium-plated iron

Flexible thermoplastic

Fluids aspirating system

Dynamic treatments for wound & and skincare

Advanced wound care Surgical incision drapeOper sense Oper �lm surgical

PlastersOper tape

Oper tape (surgical tapes)

Dry wound dressing Catheter protectionOper dres

Oper dres �lm

Oper easy

Oper �lm protect

Oper strip / Oper strip reinforced

Oper plast spot & strip

Oper cat

Oper easy IV & IV strip

Oper �lm IV & IV strip

Oper easy

Oper �lm protect

Skin & Wound Care Business UnitWorldwide woundcare market

Year 2000 Year 2011 Year 2015 Year 2018

Oper catDressing pouch for catheter protection

Easy to apply sterile self-adhesive dressing

Developed and manufactured by IHT in 2004

Oper cat is designed for the protection of:

· Temporary catheters. · Long and permanent catheristations. · Heparinazed tracts. · Jejunostomy and gastronomy nutritional drains.

Oper dresHighly absorbent dressing

Non-woven fabric with pad

Oper dres is indicated for:

· Post-op surgical wounds. · Accidental wounds. · Small cuts and scratches.

High level of absorption of body liquids.

Oper dres �lmHighly absorbent liquid impermeable dressing

Transparent polyurethane �lm with pad

Oper dres �lm is indicated for:

· Super�cial wounds. · Surgical wounds. · Small incisions, resections and lacerations. · Small abrasions and �rst-degree burns. · Wounds with mild to moderate exudate. · Securing catheters. · Whenever considered appropriate by the physician.

Impermeable to water: It offers more safety and protection of patients.It allows the patient to shower.

Transparent: Allows constant monitoring of the perilesional area.

Oper tapeElastic tape

Adhesive tape made of a non-woven fabric highly permeable to O2 and water vapour

Oper tape is a system for securing primary dressings, catheters, and tubes.

The non-woven fabric of Oper tape is adaptable, extensible, highly porous, and coated with a hypoallergenic adhesive.

· Maximum adaptability and comfort. · Safe and comfortable barrier. · Optimal attachment. · Highly transpirable.

Oper easyImpermeable to liquids and permeable to oxygen dressing

Transparent polyurethane �lm dressing

Second skin for the patient, indicated for:

· Super�cial wounds. · Surgical wounds. · Small incisions, resections and lacerations. · Protection of skin at risk. · Hypertrophic or keloid tissue. · Primary dressings �xation. · Securing catheters. · Wounds with mild-moderate exudate.

Highly breathable and easy to apply.

Oper easy IVDressing for the protection and observation of the puncture site

Oper easy IV stripDressing for securing the catheter and for the protection and observation of the puncture site

IV transparent polyurethane �lm with and without strips

Indicated for securing the catheter and for protection and observation of the puncture site

Dressings with split, designed to protect peripheral intravenous catheter sites and secure tubes or medical devices, which allow visual inspection of the puncture site without changing the dressing.

Oper easy IV and Oper easy IV strip are highly breathable, hypoallergenic, elastic and adaptable transparent polyurethane �lm surgical dressings.

Highly breathable and easy to aply.

Oper plast spot & stripSmall, discreet plasters

Small adhesive �esh-coloured strips of microperforated polyethylene �lm with hypoallergenic acrylic adhesive and non-stick, non-woven fabric pad

They are specially designed to:

· Care for and protect small cuts and abrasions. · Protect puncture sites. · Protect from dirt.

Oper plast spot Oper plast strip

Oper stripAdhesive skin sutures

Breathable non-woven polyester and polyamide fabric

Oper strip provides support that gives stability to the wound, aiding healing and keeping scarring to a minimum for:

· Super�cial or moderately-deep skin cuts. · Lacerations and surgical incisions. · Traditional sutures. · Substitute after removal of sutures.

Oper strip can remain in place for up to 7 days.

Transparent polyurethane �lm providing a sterile �eld around the area to be handled

Oper �lm surgical acts as a microbial barrier, avoiding bacterial penetration or migration

· Immobilizes skin bacteria tending to migrate to the surgical area.

· Prevents bacterial recolonization by avoiding bacterial migration.

· Prevents bacterial migration from the skin to the wound. · Allows to keep a liquid-free surgical �eld. · Prevents patient and healthcare personnel crossed- contamination.

Oper �lm surgicalSurgical �eld

High permeability and elasticity

Its elasticity enables it to �awlessly adapt to all body parts, including areas that are very dif�cult to operate on, and is even suitable for operations with a great degree of manipulation.

Transparent plastic tape

Makes positioning easier and allows for permanent vigilance.

Flexibility

The microperforated polyethylene �lm gives this adhesive tape a degree of elasticity suitable for securing to mobile body parts.

Highly porous

Its high porosity helps to maintain the integrity of the skin.

Waterproof

The polyethylene �lm and acrylic adhesive are waterproof, so the patient can shower without risk of the adhesive tape falling off.

Oper tape clearTransparent surgical tape

Oper tape paperSurgical tape for sensitive skin

Adhesive tape for application on sensitive skin

The non-woven fabric and the hypoallergenic adhesive used enable repeat applications to the skin and application on sensitive skin:

· Neonatology · Geriatrics · Paediatrics · Dialysis · Others

A highly-porous non-woven fabric

Its high porosity helps to maintain the integrity of the skin.

Thanks to an advanced production process, Oper tape paper adhesive is applied to non-woven cellulose fabric, providing high permeability to oxygen and steam.

Oper tape paper is resistant to extreme temperatures and moisture.

PIPELINE(2014 - 2015)

OPER FILMPROTECT

OPER TAPE PLAST

OPER TAPE SILK

OPERSENSE

Oper Care & White label-Bulk

Others business

Our international OTC brand for small plasters.

Finish the manufacturing process in your facilities.

IHT will send to you small plasters in bulk.

We have a variety of adhesive supports and measures.

Oper care

White-label Bulk

Oper Care

Our international OTC brand for small plasters

Iberhospitex, S.A.Avda. Catalunya, 4 . 08185 Lliçà de Vall, Barcelona, SpainTel +34 938 436 034 . Fax +34 938 436 111info@iht.es . www.iht.es

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