Http://@adams-institute.ac.uk Ken.Peach@ptcri.ox.ac.uk PAMELA Status Ken Peach * John Adams

http://www.adams-institute.ac.uk

Ken.Peach@adams-institute.ac.ukhttp://www.ptcri.ox.ac.uk Ken.Peach@ptcri.ox.ac.uk

PAMELA Status

Ken Peach*

John Adams Institute for Accelerator Science&

Particle Therapy Cancer Research Institute*

FFAG11, Oxford, September 15th 2011

Work supported by the UK Basic Technology Fund grant number EPSRC EP/E032869/1* Part of Oxford MartinSchool, University of Oxford

On behalf of the PAMELA Design Team:John Cobb, Suzanne Sheehy, Holger Witte, Takeichiro Yokoi (JAI, Oxford)Richard Fenning, Akram Khan (Brunel University, UK) Rebecca Seviour (Cockcroft Institute, Lancaster, UK)Carol Johnstone (Fermilab, USA)Mark Hill, Bleddyn Jones*, Borivoj Vojnovic (Gray Institute for Radiation Oncology and Biology, Oxford, UK) Morteza Aslaninejad, Matt Easton, Jaroslaw Pasternak (Imperial College, UK)

Jürgen Pozimski (Imperial College and STFC/RAL, UK)Neil Bliss, Carl Beard, Peter McIntosh, Susan Smith, Stephan Tzenov (STFC/DL, UK) Rob Edgecock, David Kelliher, Shinji Machida, James Rochford (STFC/RAL, UK)Roger Barlow, Hywel Owen, Sam Tygier

(University of Manchester, UK)

Ken Peach (John Adams Institute & PTCRI, Oxford) PAMELA Status FFAG11, Oxford September 15th 2011 2

Outline

PAMELAParticle Accelerator for MEdicaL Applications

• Clinical Requirements• Accelerator Technologies• PAMELA – status• Summary

Clinical Requirements

• Charged Particle Therapy (CPT)– Protons and light ions– Used to treat localised cancers

• Less morbidity for healthy tissue• Less damage to vital organs• Particularly for childhood cancers

With X-raysWith Protons“When proton therapy facilities become available it will become malpractice not to use them for children

[with cancer].”Herman Suit, M.D., D.Phil., Chair, Radiation Medicine, Massachusetts General

Hospital

CPT – why & what?

Main Clinical Requirements

Treatment Plan

should bedetermined

byclinicalneednot

limited by

AcceleratorTechnology

Accelerator Technology?

• Cyclotrons– Fixed energy extraction, difficult for Carbon at

full energy (equivalent to 1.2 GeV/c protons)• Synchrotrons

– Flexible, but too slow?• FFAG

– Flexible, rapid cycling (fixed field), variable energy … but … new technology• Scaling (Mori) & non-Scaling (Johnstone, PAMELA)

• (Compact) Linear Accelerators– e.g. Dielectric Wall Accelerators

• …• Laser-Plasma Ion accelerators

– Future …

Challenges

• The non-scaling Fixed-Field Alternating Gradient Accelerator is a new type of accelerator– Lattice?– Magnets, injection/extraction– Challenging RF– Resonance crossing?– Stability

• EMMA is a relativistic ns-FFAG• PAMELA is a non-relativistic ns-FFAG

Solutions

1. (Johnstone & Koscielniak)– Use wedge-shaped magnets

• Stabilize betatron tune• Longer straight sections

2. (Machida)• Introduce higher multipoles

• Stabilize betatron tune• Longer straight sections

See Johnstone and Koscielniak, “Tune-Stabilized Linear-Field FFAG for Carbon Therapy”, EPAC Edinburgh (2006), 2290.Johnstone: “Non-Scaling FFAG Accelerator Variants for HEP and Medical Applications”, PAC Vancouver (2009)

S. Machida, “FFAGs for proton acceleration”, FFAG'08 workshop, Manchester, 2008

Can an EMMA-like ring work for protons?

http://www.adams-institute.ac.uk

Ken.Peach@adams-institute.ac.ukhttp://www.ptcri.ox.ac.uk Ken.Peach@ptcri.ox.ac.uk

PAMELA

STATUS

PAMELA Layout

Carbon source & injection

Proton source & injection

Carbon ring

Transfer line

Extraction

Proton ring

ION SOURCES

Ion sources

C4+ trajectories through the RFQ C4+ final energy

Carbon RFQ Parameters

E-field frequency 200MHzEI 8 keV/uEf 382 keV/uTransmission 75%RFQ length 2.4mElectrode potential 80 kV

Ion Sources: another option

Winkelmann et al. Rev. Sci. Instrum. 79, 02A331 2008

The Heidelberg C4+/H3+ ECRIS Source for HIT

LATTICE

Packing Factor

No. cells

Radius Orbit Excursion

Straight Section

0.48 12 6.251 m 0.176 m 1.702 m

Present Lattice – Proton Ring

• Proton ring (30 to 250 MeV)– Carbon requires second ring– Work in progress

• non-scaling, non-linear lattice– Tune-stabilisation

• Principle idea:– Start with scaling FFAG– Relax scaling law

• Rectangular CF magnets • Aligned on straight line• Multipoles up to octupole

– Results in FFAG with...• Small orbit excursion (<172 mm)• Compact magnets• No/little tune shift

• 12 cells, FDF-triplet– Straights: 1.7 m– Sufficient space

• Injection/extraction • RF

Working Point and Tunes

• Working point– High k (38)

• minimize orbit excursion• Machine tune variation

(cell tune variation*12): [decapole]

– νx within 0.0476 – νy within 0.0528– Well within an integer!

• Beam sensitivity– Amplification factor 5.8 (h)–

9.5 (v)(A = orbit distortion [mm] /

1σ alignment error [mm])

horizontal vertical

Proton Ring

Working Point and Tunes Carbon Ring

• Working point– Radius 9.3m– Packing factor 0.63– High k 42– orbit excursion 0.217m

• Machine tune variation (cell tune variation*12): [decapole]

– νx within 0.130 – νy within 0.117

horizontalvertical

MAGNETS

Magnetic Lattice

Magnet Requirements

• Non-scaling, non-linear FFAG– Multipoles up to decapole

• Challenges– Maximum field (4.25T)– Length restriction (314 mm)– Required bore (>250 mm)

• Magnet options– n/c Iron cored magnets– Superferric coils– S/C cos(q) magnets– S/C Double-helix coils

• Choose: Double-helix coils

Double-Helix Principle

)cos(tan

)cos(:

)sin(:

Current density:

Helix 1 Helix 2

nconstJz

Double-helix coil: Smart way of creating a cosine-theta magnetMain advantage for PAMELA: No coil end problem

Double-Helix

High field quality

Patent Application GB 0920299.5

ACCELERATION

RF System • 1kHz repetition rate ~ 100kV/turn

• Drift space ~1.7m

• Target energy gain:

– ~16kV/turn/cavity

• Challenges: – duty cycle, Modulation, gradient

• Ferrite loaded cavity – baseline: ISIS 2nd harm. cavity

• Relatively high Q (~100)• sufficient accelerating field• h=10 ? • heat load @ 1kHz ~100kW/cavity

• Development started– Ferrite property measurement

• Q-value, FM rate dependence

INJECTION & EXTRACTION

PAMELA: Beam extraction

• Kicker system• Vertical extraction• Advantages over horizontal extraction

– weaker field • <0.06T~1m (hor: 2.9 kG)

– Peak voltage: • 30kV (hor: 446 kV for movable C-

• R&D issues– Large aspect ratio kicker (185x26 mm2)

• kicker inductance?– Kicker reliability

• @1 kHz, 10h/day, 5d/week ~10B pulses/y– Scaling to carbon ring

• 0.16T, 78kV

230MeV (Bkicker:0.6kgauss)

@kicker

CO@septum

septum

FDF FDF

Kicker#1 Septum

Kicker specification at injection

Emittance of circulating beam at injection 10 mm mrad (unnormalized)

Vertical beta function at injection 1m

Orbit separation at septum 30mm

Fall-off time 250ns (traveling wave)

Acceptable total field error (B/B) 0.1

Kicker specification at extraction

Emittance of circulating beam at extraction 10 mm mrad (unnormalized)

Vertical beta function at injection 1m

Orbit separation at septum 30mm

Fall-off time 100ns (traveling wave)

Acceptable total field error (B/B) 0.02

Kicker specification

• Kicker length <1m

Kicker Performance (proton ring)

Septum

BEAM TRANSPORT & GANTRY

Beam Transport

• Need an FFAG beam transport

0.2m 0.2m 3.6m

Gantry Design

Beam Transport and Gantry

FFAG-like achromatic beam transport & gantry

Next steps

1. Seek component prototype funding• Main ring magnets• RF• Kickers• Carbon RFQ

2. Seek machine funding• Demonstrator for CPT

Summary

• The conceptual design of a Charged Particle Therapy (protons and light ions) accelerator using a non-linear non-scaling FFAG has been presented– A realistic lattice design– Feasible magnets & RF– Ion source, injection, extraction – Beam transport & gantry

• Next steps require prototyping

Http://@adams-institute.ac.uk Ken.Peach@ptcri.ox.ac.uk PAMELA Status Ken Peach * John Adams

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