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How to search for possible drug interactions on the internet?
SCART online – ITM 2007
Drug interaction webpages
In the following presentation you will learn how to search for drug interactions on interactive webpages and what information you can find on static webpages. Here a selection of possible sources of information:
1. http://www.hivinsite.com/arvdb?page=ar-00-022. http://www.medscape.com/druginfo/druginterchecker (this
webpage requires registration, however it is for free!)3. http://www.hiv-druginteractions.org/4. http://www.tthhivclinic.com/interact_tables.html5. http://www.thebody.com/treat/interactions.html
If you would like to exclude a possible drug interaction, it is highly recommended to check at least two different websites!
Selected webpages for drug interactions
1. www.hivinsite.com/arvdb?page=ar-00-02
This is an interactive webpage where you can make a query. The next slides show you how to do a query to check for a possible drug-drug interaction.
Selected webpages for drug interactions
This option you choose if you want to know a drug-interaction with a certain antiretroviral drug
This option you choose if you want to know a drug-interaction with a drug which is not a antiretroviral drug
This option you choose if you want to get an overview of the drug-interactions of a certain drug class
Step 1: you select the option “search by antiretroviral drug” Example:
you would like to check if the combination of nevirapine and ketoconazole could lead to a possible drug-interaction
To place a query you need to know the name of the active molecule of the drug (generic name, e.g. nevirapine). In case you have just the brand name (e.g. Viramune) you could check the following webpages first to find out the generic name: www.google.com, www.drugs.com
Step 2: you select “nevirapine” in the list of antiretroviral drugs
Step 3: you select “by individual drug” to check the interaction with
ketoconazole
Step 4: you press the button “submit”
Step 5: you select “ketoconazole” and press the button “submit” at the
end of the list
Would you co-administer ketoconazole with nevirapine?
NO, they advise not to co-administer these two drugs together
2.http://www.medscape.com/druginfo/druginterchecker
This is an interactive webpage where you can make a query. The next slides show you how to do a query checking a possible drug-drug interaction.
On this webpage you can search by generic drug name or by the brand name.
Selected webpages for drug interactions
We are taking the same example:
you would like to check if the combination of nevirapine and ketoconazole could lead to a possible drug-interaction
Step 1: this database is working with generic names or with brand names,
so you can type “nevirapine” or “Viramune” in the text box and press
“go”
Step 2: one or more options are shown in the result box, you select
the option you want to check
Step 3: you “click to add” and the chosen option appears in the patient
regimen box
This webpage is requiring registration first, however it is for free!
Step 4: you type “ketoconazole” (or Nizoral) in the text box and press
“go”
Step 5: you select the option you are interested in and press “click to add”
Step 6: the combination of nevirapine and ketoconazole could
lead to interactions, for more information press the button “click
here”
Here the result of your query with detailed information and severity level of the drug interaction!
3. http://www.hiv-druginteractions.org/
This is an interactive webpage where you can make a query. The next slides show you how to do a query to check for a possible drug-drug interaction.
Selected webpages for drug interactions
Click here to access the drug-interaction charts
You can choose between different options, depending on what you
would like to check!
To place a query you need to know the name of the active molecule of the drug (generic name, e.g. nevirapine). In case you have just the brand name (e.g. Viramune) you could check the following webpages first to find out the generic name: www.google.com, www.drugs.com
We are taking the same example:
you would like to check if the combination of nevirapine and ketoconazole could lead to a possible drug-interaction
Step 1: you choose option 1
Step 3: you click on “next”
Step 2: you click on “nevirapine”
Step 4: as ketoconazole is an antifungal, you click on “antifungals”
Step 5: you click on next
Step 6: you click on “ketoconazole”
Step 7: you click on next
Step 8: you can see in the description above that
ketoconazole should not be coadministered with nevirapine; if you click on the red button you will
get more detailed information
Here you get the result of your query with detailed information!
4.http://www.tthhivclinic.com/interact_tables.html
5.http://www.thebody.com/treat/interactions.html
These are static webpages containing drug interaction tables. The next slides show you some examples of what information you get.
Selected webpages for drug interactions
This drug-interaction webpage is static and here
you can access drug-interaction tables for
example
You are at the end of the presentation.
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