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Giant Cell Tumor of Bone
I K B A L A D I T A K W A A .
K O A S R A D I O L O G I R S U D 4 5 K U N I N G A N
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Giant Cell Tumor
80% jinak, 20% ganas
Sinonim: osteoclastoma
Insiden: 58% tumor tulang ganas, 15% tumor tulangjinak
Jinak predominant untuk wanita, ganas biasanya lakilaki
Usia: 2040 th
Rasa nyeri dan gangguan gerak sendi
Femur distal, tibia proksimal, radius distal, humerusproksimal (os sacrum 8%)
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Location
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Radiologik
Lesi di metafise meluas kearah subartikuler pada epifise
sudah menutup
Lesi lusen eksentris Sifat ekspansif dengan soap bubble appearance
Kadangkadang sulit membedakan antara jinak dan
ganas
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Radiology
Lytic lesion
Epipyseal
Eccentric or central Narrow zone transition
Cortical thinning
expansile No sclerotic margin
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DDx
Consider: Age & Location
Fibrogenic/Telangiectatic Osteosarcoma
MFH
Brown tumor
Chondroblastoma
ABC
Chondromyxoid fibroma (rare)
Mets / Myeloma
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