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Erasmus MC Incubator
Michel Bergh PhD
Director
Erasmus MC Technology Transfer Office
Project leader, Incubator
May 28, 2013
Erasmus MC
Largest UMC in the Netherlands
Centrally located, Sophia Children’s
Hospital, Daniel Den Hoed Cancer Clinic,
Havenziekenhuis
Total budget € 1.2 B
14,000 employees
~ 3,100 students
~1,000 grad students
> 1,500 medical and scientific staff
Research budget €138 M/yr
Desiderius Erasmus (1466-1536)
Erasmus MC : Patient Care
Top clinical and referral patient care (last resort referrals)
Regional center
36.000 admissions/yr (1,200 beds)
> 500.000 visits outpatient clinics
Erasmus MC : Research Key Areas
Cardiovascular
Oncology
Virology
Cell Biology & Genetics
Endocrinology
Immunology & Haematology
Neurosciences
Pediatrics
Medical Technology/Imaging
Epidemiology and Public Health
Health Policy and Management
5
Technology Transfer Mission
It is our mission to transfer Erasmus MC’s research results
and technologies into useful products and services, thereby
creating value for society in general and health care in
particular, and income to support research, education and
patient care
Technology Transfer Scope
Broad spectrum of startups From e-learning to AML diagnostics
Promising new licenses From image analysis to antivirals
New software applications Smart phone registration/itemization of patient care activities
Innovations in patient care Improved care AND cost reductions
Geboortecentrum
Diabetes Station
Smart phone pre-conception consultation
A-Z: from Invention Disclosure to License or Start-up
Innovative approach for photodynamic therapy using nanoparticles. Licensed to start-up Nano4Therapy
Novel protease inhibitor platform with broad applications in virology Company formation in progress
Predicting eye and hair color from crime scene DNA Diagnostic test in forensic field.
Licensed
Quantitative MRI image analysis for improved diagnosis
Licensed to start-up company, funded by multinational and EZ (Innovatiekrediet)
Technology Transfer: Success Stories
Financial success: Pompe’s disease
Therapeutic enzyme (α-glucosidase) for hereditary disease
Erasmus MC production technology
Significant royalty income for Erasmus MC and inventors
Business Model Success: Viroclinics
Healthy business in providing vaccine testing services
Societal success: Geboortecentrum (Birthing Center)
Life saving by close proximity to OR
Physical distance: 2 minuten
Technology Transfer: Patient Care Innovations
Das Abklebebuch/Plakboek
Improving toddler
compliance with orthoptic
eye patches for amblyopia
Lachgas Protocol
Delivery under sedation by nitric oxide
Developed by Erasmus MC
Obstetrics, licensed to Careyn
Maternity Care and other midwife
providers
Geboortecentrum (Birthing
Center)
Technology Transfer: Patient Care Innovations
DiabetesStation
Integrated self-diagnosis cabin for
diabetes patients
Slimmer Zwanger
Smartphone app for pre-pregnancy
consultation
Technology Transfer Office KPIs
KPIs 2008 2009 2010 2011 2012
Invention
disclosures
56 48 38 62 38
Patent
applications
11 12 11 15 13
Granted
patents
14 20 28 15 12
Total patent
(application)s
151 163 163 172 163
License
agreements
3 4 10 14 15
Licensing
income
€ 2.0 M
€ 2.1 M € 2.2 M € 2.7 M € 2.8 M
Start-up
companies
10 6 3 1 5
Total # companies in portfolio 20
Total # agreements reviewed (SRAs, consortium agmts. etc.) ~ 640
Erasmus MC Start-ups
Skyline Diagnostics
Harbour Antibodies
Cavadis
Viroclinics
Vironovative
Arcarios
DiabetesStation
Nano4Therapy
AgenD
Quantib
ABCDEsim
Luminostix
River D International
Skintec
IDMC
CQ Path
Practocol
Photonics Healthcare
CardiogenX
Fagotrace
Erasmus MC Incubator
First Erasmus MC Incubator housed in Faculty Building
> 5 tenants
Renovation of ’60s building
Need for new space
Office tower “Europoint” on Marconiplein
Built in 1975
Original designation office space
Renovated for use by high tech firms
Renamed “Rotterdam Science Tower”
Erasmus MC Incubator
EFRO support essential to create unique laboratory facilities
Addresses need for lab space
Scarcety of laboratory facilities in the region
ML1, ML2 safety level
Erasmus MC Incubator moves into Rotterdam Science Tower
Offering mix lab/office space
Creating turnkey solutions for start-up needs
Sign lease on Monday, move in Tuesday, start work on Wednesday
Erasmus MC Incubator
Specifically companies with connection to the Erasmus MC
Committee for approving the start-up acceptance
Start-up facilities for fast growth
Physical: good location close to Erasmus MC
“Soft” benefits: expert external advice allowing focus on core business
Providing a safe haven for 3 years in the right neigborhood
18th floor: Erasmus MC Incubator
1st – 7th floor: Zadkine College (technicians, interns)
10th floor: Start-up Campus
19th – 20th floor: Viroclinics
After 3 years, other facilities are available 10 feet away
Erasmus MC creates 800 m2 Incubator
Mixed lab and office space
Turn-key solutions
MLI, MLII safety level
etc.
Supported by
Erasmus MC
EFRO
City of Rotterdam
Fortress Real Estate
Managed by
Carola Immerzeel-Goosens, Duko Drijfhout
Erasmus MC Incubator
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