Chapter 16: The Lymphatic System and Lymphoid Tissue

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Chapter 16: The Lymphatic System and Lymphoid Tissue. Overview. Key Terms. adenoidlymphadenopathylymphoma chylelymphangitisspleen lymphlymphatic ductthymus lymphadenitislymph nodetonsil. The Lymphatic System. System of tissues and vessels Scattered throughout the body - PowerPoint PPT Presentation

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Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Chapter 16:The Lymphatic Systemand Lymphoid Tissue

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Overview

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Key Terms

adenoid lymphadenopathy lymphoma

chyle lymphangitis spleen

lymph lymphatic duct thymus

lymphadenitis lymph node tonsil

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Cohen: Memmler’s The Human Body in Health and Disease

The Lymphatic System

• System of tissues and vessels

• Scattered throughout the body

• Services almost all regions

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Cohen: Memmler’s The Human Body in Health and Disease

Functions of the Lymphatic SystemLearning Outcome

1.List the functions of the lymphatic system.

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Cohen: Memmler’s The Human Body in Health and Disease

Functions of the Lymphatic System

Three Main Functions

•Fluid balance (lymph)

•Protection from infection

•Absorption of fats

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Cohen: Memmler’s The Human Body in Health and Disease

Functions of the Lymphatic System

✓Checkpoint

16-1 What are the three functions of the lymphaticsystem?

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphatic Circulation

Learning Outcomes

2.Explain how lymphatic capillaries differ from blood capillaries.

3.Name the two main lymphatic ducts and describe the area drained by each.

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphatic Circulation

• One-way system

• Begins in tissues

• Ends in bloodstream

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-1 The lymphatic system in relation to the cardiovascular system.

What type of blood vessel receives lymph collected from the body?

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphatic Circulation

Lymphatic Capillaries

•Capillary walls (endothelium) are flattened epithelial cells.

•They are more permeable than blood capillaries.

•Overlapping cells form one-way valves.

•They arise blindly (closed at one end).

•Lacteals absorb digested fats.

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-2 Lymphatic drainage in the tissues.

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphatic Circulation

Lymphatic Vessels

•Superficial and deep sets

•Right lymphatic duct

•Thoracic duct (left lymphatic duct)

– Cisterna chyli

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-3 Vessels and nodes of the lymphatic system.

What are some nodes that receive lymph drainage from the breast?

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphatic Circulation

Movement of Lymph

•Movement of lymph toward heart caused by:

– Valves in lymphatic vessels

– Contraction of lymphatic vessels

– Skeletal muscle contraction

– Breathing

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Cohen: Memmler’s The Human Body in Health and Disease

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Lymphatic Circulation

✓Checkpoints

16-2 What are the two differences between bloodcapillaries and lymphatic capillaries?

16-3 What are the two main lymphatic vessels?

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphatic Circulation

?Pop Quiz

16.1 Which of the following is NOT characteristic of lymphatic vessels?

A) They have thin walls.

B) They are blind-ended.

C) They can contract to propel lymph.

D) They transport lymph to the tissues.

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Lymphatic Circulation

?Pop Quiz Answer

16.1 Which of the following is NOT characteristic of lymphatic vessels?

A) They have thin walls.

B) They are blind-ended.

C) They can contract to propel lymph.

D) They transport lymph to the tissues.

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

Learning Outcome

4.List the major structures of the lymphatic system and give the locations and functions of each.

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

• Distributed throughout the body

• Makes up specialized organs of lymphatic system

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-5 Location of lymphoid tissue.

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

Lymph Nodes

•Cervical nodes

•Axillary nodes

•Tracheobronchial

•Mesenteric nodes

•Inguinal nodes

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-3 Vessels and nodes of the lymphatic system.

What are some nodes that receive lymph drainage from the breast?

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-4 Lymph nodes.

What type of lymphatic vessel carries lymph into a node? What type of lymphatic vessel carries lymph out of a node?

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

The Spleen

•Cleanses blood

– Filtration

– Phagocytosis

•Destroys old red blood cells

•Produces red blood cells before birth

•Is a reservoir for blood

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

The Thymus

•Plays a key role in early immune system development

•Produces thymosin

– Develops T-lymphocyte cells

– Promotes lymphocyte growth

– Promotes lymphoid tissue activity

•Shrinks after puberty

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

The Tonsils

•Remove contaminants and trap pathogens

•Palatine tonsils

•Pharyngeal tonsil (adenoids)

•Lingual tonsils

•Surgery to treat if recurrent infection or enlarged tonsils make swallowing or breathing difficult

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-6 Location of the tonsils.

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

Other Lymphoid Tissue

•Appendix

•Mucosal-associated lymphoid tissue (MALT)

•Gut-associated lymphoid tissue (GALT)

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Cohen: Memmler’s The Human Body in Health and Disease

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

✓Checkpoints

16-4 What is the function of the lymph nodes?

16-5 What is filtered by the spleen?

16-6 What kind of immune system cells develop in the thymus?

16-7 What is the general location of the tonsils?

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Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

?Pop Quiz

16.2 Lymph from the arm and breast passes through which of the following?

A) Inguinal nodes

B) Cervical nodes

C) Axillary nodes

D) Tracheobronchial nodes

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Lymphoid Tissue

?Pop Quiz Answer

16.2 Lymph from the arm and breast passes through which of the following?

A) Inguinal nodes

B) Cervical nodes

C) Axillary nodes

D) Tracheobronchial nodes

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Disorders of the Lymphatic System

Learning Outcome

5.Describe the major lymphatic system disorders.

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Cohen: Memmler’s The Human Body in Health and Disease

Disorders of the Lymphatic System and Lymphoid Tissue

Disorders Related to Infection

● Lymphadenopathy

● Lymphadenitis

● Infectious mononucleosis

Lymphedema

● Elephantiasis

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-7 Infectious mononucleosis.

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-8 Lymphangitis.

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Cohen: Memmler’s The Human Body in Health and Disease

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Disorders of the Lymphatic System and Lymphoid Tissue

• Splenomegaly

• Lymphoma

– Hodgkin lymphoma

– Non-Hodgkin lymphoma

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Cohen: Memmler’s The Human Body in Health and Disease

Figure 16-9 Reed-Sternberg cell.

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Cohen: Memmler’s The Human Body in Health and Disease

Disorders of the Lymphatic System and Lymphoid Tissue

✓Checkpoints

16-8 What is lymphadenopathy?

16-9 What is lymphoma and what are the two examplesof malignant lymphoma?

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

Disorders of the Lymphatic System and Lymphoid Tissue

?Pop Quiz

16.3 What is Hodgkin lymphoma?

A) A benign tumor of the lymph nodes

B) A malignant tumor of the lymph nodes

C) A benign tumor of the spleen

D) A malignant tumor of the spleen

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Cohen: Memmler’s The Human Body in Health and Disease

Disorders of the Lymphatic System and Lymphoid Tissue

?Pop Quiz Answer

16.3 What is Hodgkin lymphoma?

A) A benign tumor of the lymph nodes

B) A malignant tumor of the lymph nodes

C) A benign tumor of the spleen

D) A malignant tumor of the spleen

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Cohen: Memmler’s The Human Body in Health and Disease

Case Study

Learning Outcome

6. Describe the spleen’s functions and the consequences of its removal.

 

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Cohen: Memmler’s The Human Body in Health and Disease

Case Study

Functions of the Spleen

•Filters blood

•Removes worn-out old blood cells

•Acts as a large lymph node, detecting and fighting disease-causing organisms

Consequences of Splenectomy

•Liver will take over blood filtration and RBC removal

•Greater risk of infection

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Cohen: Memmler’s The Human Body in Health and Disease

Word Anatomy

Learning Outcome

7.Show how word parts are used to build words related to the lymphatic system.

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Cohen: Memmler’s The Human Body in Health and Disease

Word Anatomy

Copyright © 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins

Cohen: Memmler’s The Human Body in Health and Disease

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