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BerryPEPProduct Technical Report
INCI name: Panax Ginseng Berry Extract, Lactobacillus/Ginseng Root Ferment Filtrate
BerryPEP
Introduction of Our Peptide Products.
BerryPEPINCI Name : Panax Ginseng Berry Extract, Lactobacillus/Ginseng Root Ferment Filtrate
Scientific name Panax ginseng C. A. Meyer
Kingdom Plantae
Division Anthophyta
Class Dicotyledoneae
Order Umbelliferae
Distribution area Korea, China, Russia
Habitat/Home
It is native to an area ranging from 30° to 48° Nort
h latitude, and native to three areas; Korea (33.7° t
o 43.21°), Manchuria (43° to 47°) in China, and the
Siberian Maritime Territory (40° to 48°).
Size Height 60cm
Classification of domesti
c varieties and overseas
varieties
Korean ginseng is called Goryeo (Korean) ginseng
and written in ‘蔘’.
Foreign ginseng is written into ‘參’. For example, A
merican ginseng (Panax quinquefolium,花旗參), Jap
anese ginseng (Panax japonicum, 東洋參), Chinese
ginseng (Panax notoginseng, 關東參)
Content 100% pH 5.5 ~ 7.5
Appearance Clear yellowsh Liquid Specific Gravity 0.98 - 1.20
Odor Characteristic Preservative Free
Introduction of Our Peptide Product
BerryPEP
A product made by separating and fermenting peptide, a
functional ingredient, from Ginseng Berry
Ginseng Berry, which is borne only once every four years, is
rich in essential nutrients such as saponin and peptides.
Ginseng contains about two to three times more active
ingredients in its fruits than the roots.
Developed as a low-irritating material specialized in various
cosmetic formulations by multiplying the efficacy by fermenting
highly functional lactic acid bacteria.
A product that is especially effective in anti-wrinkle and anti-
aging and that can be applied to any formulation
Application : Anti-Oxidant, Anti-aging
Ginseng Berry
Keywords “Fruit of the youngest time”, “only once”, “rarity”, “ginsenoside”, “modern elixir plant”
Introduction of Our Peptide Product
BerryPEP : Cell regeneration
Results: BerryPPEP is artificially scared and rapidly recovered (reduced free space) depending on concentration when
processing skin cells (HACAT, Keratinocyte)
0 hr
12 hr
24 hr
control 5% 10% 20%
100%
83%
61.8%
100%
79.3%
55.5%
100%
65.3%
47.5%
100%
51.3%
32.5%
Introduction of Our Peptide Product
BerryPEP : Reference
Fig. 3. Ginseng components have antioxidative activities. Ginseng root, ginseng berry, and syringaresinol have DPPH radical-scavenging activity (A) and H2O2 scavenging activity(B). Data are presented are the mean SD. * p < 0.05 by two-tailed Student t test.(해설) Fig. 3. 인삼성분은산화방지기능이있다. 인삼뿌리, 인삼열매 그리고시린가레시놀은 DPPH radical-scavenging activity, H2O2 scavenging activity 가있음을확인하였다.
GR: Ginseng RootGB: Ginseng BerrySYR:Syringaresinol
Effects of Korean ginseng berry on skin antipigmentation and
antiaging via FoxO3a activationJ Ginseng Res 2017;41:277e283
GR: Ginseng RootGB: Ginseng BerrySYR: Syringaresinol
Fig. 5. Ginseng components have potent Anti-aging activity(A, B). induce a life span extension in the Caenorhabditis elegans wild type N2 strain. The survival curves (A) and the mean life span (B)(C, D). Ginseng components decrease lipofuscin accumulation in passaged human dermal fibroblasts(해설) Fig. 35 인삼성분은 안티에이징효과가있으며 C.elegans의수명연장효과와사람의피부세포 (fibroblast)에서 lipofuscin accumulation 을억제하여 Anti-aging 효과를보인다.
Introduction of Our Peptide Product
BerryPEP : ReferenceEffects of Korean ginseng berry on skin antipigmentation and
antiaging via FoxO3a activationJ Ginseng Res 2017;41:277e283
Introduction of Our Peptide Product
BerryPEP: Efficacy Test
BerryPEP has a concentration-dependent antioxidant effect,which is beneficial to the skin.
0%
20%
40%
60%
80%
100%
DP
PH
RA
DIC
AL
SCA
VEN
GIN
G(%
)
DPPH radical scavenging assay(BerryPEP)
-28.2% -45.3% -72.5%-53.2%
1.0% 2.0% 4.0% 8.0%control
Tested by A&PEP Laboratory
Introduction of Our Peptide Product
BerryPPEP has concentration-dependent ellastase activity-suppressing effects It is effective for wrinkle improvement and anti-aging.
0%
20%
40%
60%
80%
100%
ELA
STA
SE IN
HIB
ITIO
N (
%)
Elastase inhibition assay(BerryPEP)
1.0% 2.0% 4.0% 8.0%Control
-27.6% -38.3% -62.1%-53.8%
Introduction of Our Peptide Product
BerryPEP: Efficacy Test
BerryPEP has concentration-dependent collagenase activity-suppressing effects and is effective for wrinkle improvement and anti-aging
0%
20%
40%
60%
80%
100%
CO
LLA
GEN
ASE
INH
IBIT
ION
(%)
Collagenase inhibition assay(BerryPEP)
1.0% 2.0% 4.0% 8.0%Control
-29% -35% -45% -59%
Introduction of Our Peptide Product
BerryPEP: Efficacy Test
BerryPEP is effective for wrinkle improvement and anti-aging, which are concentration-dependently effective for MMP-1 activity suppression.
0%
20%
40%
60%
80%
100%
MM
P1
EX
PR
ESSI
ON
(%
)
MMP-1 inhibition assay(BerryPEP)
7%29% 41% 51%
1.0% 2.0% 4.0% 8.0%Control 0%
Introduction of Our Peptide Product
BerryPEP the simplified human body application test
• Ages : 40s – 50s
• Subjects : improving wrinkles around the eyes
• Periods : 8 weeks (checking in duplicate)
• Concentration:
- Test group “applying BerryPEP 10% cream”
- Control group “non-applying BerryPEP cream”
• Methods
1) 8 weeks of clinical trial, using the product at least 5
times a week
2) Using 7 times a week depending on skin age and
wrinkles
0
65
75
0
20
40
60
80
0W 4W 8W
Wrinkle improvement rate of subjects after 4W : 65.0%
Introduction of Our Peptide Product
As a result of the simplified human body application test0W 4W 8W
Test grou
p
Contro
l gro
up
4W8W
4W
8W
0W
0W
it is confirmed that BerryPEP improved the length and depth of wrinkles in the test group compared to the control group.
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