Be488 Major Sem2 04

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8/14/2019 Be488 Major Sem2 04

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8/14/2019 Be488 Major Sem2 04

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3 (a) Brie11yexplain rl1\;tf)!!owing terms' - (i) Mutations or subsriIUtionrates: (ji) lnde1s

and p~l;'ltduge!lI;~. (iil) Synonymous and !\~J/Jsynony:nUllS ~llbsliwtions; and

Ov) Traw;ition \5 Transversions (O.5X4==2marks)(b) Briefly discuss the Juke's Canter mode! for es!irnaringthe actual substitution rates

."",.. betweentwo sequencesfromtheobs$3rvedubstirurioffrates. (3 '.narks)4. Write a brief note 01' ~he following. - (i) Promoterelementsof ProKaryotes,ij)Promoter elements \.,fEucaryotes; (iii)GC contents in Prokaryotes and Eucarymes;(iv) Isochores (2X4==8marks)

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