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A Goat on Bald Mountain Case 05-1829. Thomas E. Cecere North Carolina State University. Signalment/History. Castrated male adult mixed-breed goat Complete shed in spring for past several years – hair regrows over the summer Most recent episode – no hair regrowth - PowerPoint PPT Presentation
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A Goat on Bald MountainCase 05-1829
Thomas E. CecereNorth Carolina State University
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Signalment/History Castrated male adult mixed-
breed goat
Complete shed in spring for past several years – hair regrows over the summer
Most recent episode – no hair regrowth
Progressive ptyalism starting in spring Presented at SEVPAC 2008 –
Permission granted for use on SEVPAC website only
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Morphologic DiagnosisSalivary gland: Diffuse, severe lymphocytic and eosinophilic sialoadenitis with atrophy and interstitial fibrosis
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Thymoma associated diseases Dry mouth (Sjogren Syndrome), alopecia
areata, myesthenia gravis and others in humans
Sjogren Syndrome Keratoconjunctivitis sicca, xerostomia Immune-mediated destruction of lacrimal and
salivary gland Primary vs. secondary (rheumatoid arthritis, SLE,
polymyositis, scleroderma, thymoma)
Xerostomia vs. Ptyalism in this case?Presented at SEVPAC 2008 –
Permission granted for use on SEVPAC website only
Alopecia Areata Autoimmune skin disease
Non-scarring alopecia Lymphocytic targeting of anagen hair bulbs
Associated with thymoma in humans
Alopecia Universalis
Thymoma associated exfoliative dermatitis
Cats, rabbits Lymphocytic mural folliculitis
Rottenberg S et al. Thymoma-associated exfoliative dermatitis in cats. Vet Pathol. 2004 Jul;41(4):429-33.
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Acknowledgements Keith Linder Kristi Mozzachio NCSU Histology
Lab – Sandra Horton
Arnaud, Arun, Danielle, Crystal, Midori, Sally
Presented at SEVPAC 2008 – Permission granted for use on
SEVPAC website only
Questions?
Questions?Presented at SEVPAC 2008 –
Permission granted for use on SEVPAC website only
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